Predicting the functional consequences of genetic variants in co-stimulatory ligand B7-1 using in-silico approaches.

Mathur, Riya; Sharma, Loveena; Dhabhai, Bhanupriya; Menon, Athira M; Sharma, Amit; Sharma, Narendra Kumar; Dakal, Tikam Chand

Mathur, Riya; Sharma, Loveena; Dhabhai, Bhanupriya; Menon, Athira M; Sharma, Amit; Sharma, Narendra Kumar; Dakal, Tikam Chand.

Afiliação

Mathur R; Department of Biosciences, Manipal University Jaipur, Jaipur 303007, Rajasthan, India.
Sharma L; Department of Biosciences, Manipal University Jaipur, Jaipur 303007, Rajasthan, India.
Dhabhai B; Genome and Computational Biology Lab, Department of Biotechnology, Mohanlal Sukhadia University, Udaipur 313001, Rajasthan, India.
Menon AM; Genome and Computational Biology Lab, Department of Biotechnology, Mohanlal Sukhadia University, Udaipur 313001, Rajasthan, India.
Sharma A; Department of Integrated Oncology, University Hospital Bonn, Bonn, Germany; Department of Neurology, University Hospital Bonn, Bonn, Germany.
Sharma NK; Department of Bioscience and Biotechnology, Banasthali Vidyapith, Tonk 304022, Raj., India.
Dakal TC; Department of Biosciences, Manipal University Jaipur, Jaipur 303007, Rajasthan, India; Genome and Computational Biology Lab, Department of Biotechnology, Mohanlal Sukhadia University, Udaipur 313001, Rajasthan, India. Electronic address: tikam260707@gmail.com.

Hum Immunol ; 82(2): 103-120, 2021 Feb.

Article em En | MEDLINE | ID: mdl-33358455

Assuntos

Linfócitos B/imunologia; Antígeno B7-1/genética; Antígenos CD28/metabolismo; Ativação Linfocitária/genética; Linfócitos T Auxiliares-Indutores/imunologia; Imunidade Adaptativa/genética; Antígeno B7-1/metabolismo; Proliferação de Células/genética; Biologia Computacional; Conjuntos de Dados como Assunto; Humanos; Mitose/imunologia; Polimorfismo de Nucleotídeo Único/imunologia; Linfócitos T Auxiliares-Indutores/metabolismo

Palavras-chave

B7-1; CD80; SNP analysis; SNPs; Sequence homology-based analysis; Structural homology-based analysis

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Linfócitos B / Ativação Linfocitária / Linfócitos T Auxiliares-Indutores / Antígeno B7-1 / Antígenos CD28 Tipo de estudo: Prognostic_studies / Risk_factors_studies Limite: Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article

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