Behavioral Deficits and Brain &#945;-Synuclein and Phosphorylated Serine-129 &#945;-Synuclein in Male and Female Mice Overexpressing Human &#945;-Synuclein.

Gabrielyan, Lilit; Liang, Honghui; Minalyan, Artem; Hatami, Asa; John, Varghese; Wang, Lixin

Behavioral Deficits and Brain α-Synuclein and Phosphorylated Serine-129 α-Synuclein in Male and Female Mice Overexpressing Human α-Synuclein.

Gabrielyan, Lilit; Liang, Honghui; Minalyan, Artem; Hatami, Asa; John, Varghese; Wang, Lixin.

Afiliação

Gabrielyan L; CURE/Digestive Disease Research Center, Med/Digestive, David Geffen Medical School, UCLA, Los Angeles, CA, USA.
Liang H; CURE/Digestive Disease Research Center, Med/Digestive, David Geffen Medical School, UCLA, Los Angeles, CA, USA.
Minalyan A; CURE/Digestive Disease Research Center, Med/Digestive, David Geffen Medical School, UCLA, Los Angeles, CA, USA.
Hatami A; Drug Discovery Lab, Department of Neurology, UCLA, Los Angeles, CA, USA.
John V; Drug Discovery Lab, Department of Neurology, UCLA, Los Angeles, CA, USA.
Wang L; CURE/Digestive Disease Research Center, Med/Digestive, David Geffen Medical School, UCLA, Los Angeles, CA, USA.

J Alzheimers Dis ; 79(2): 875-893, 2021.

Article em En | MEDLINE | ID: mdl-33361597

Assuntos

Encéfalo/metabolismo; alfa-Sinucleína/metabolismo; Animais; Comportamento Animal; Encéfalo/patologia; Química Encefálica; Ensaio de Imunoadsorção Enzimática; Feminino; Humanos; Masculino; Camundongos; Camundongos Endogâmicos C57BL; Camundongos Transgênicos; Fosforilação; Serina/metabolismo; Fatores Sexuais; alfa-Sinucleína/análise

Palavras-chave

behavior; brain; mouse; phosphorylated serine-129 α-synuclein; synucleinopathy; α-synuclein

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Encéfalo / Alfa-Sinucleína Limite: Animals / Female / Humans / Male Idioma: En Ano de publicação: 2021 Tipo de documento: Article

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