Colorectal cancer prompted adipose tissue browning and cancer cachexia through transferring exosomal miR-146b-5p.

Di, Wenjuan; Zhang, Wenling; Zhu, Bei; Li, Xiaolin; Tang, Qiyun; Zhou, Yichan

Di, Wenjuan; Zhang, Wenling; Zhu, Bei; Li, Xiaolin; Tang, Qiyun; Zhou, Yichan.

Afiliação

Di W; Department of Geriatrics, The First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu, PR China.
Zhang W; Department of Gastroenterology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu, PR China.
Zhu B; Department of Geriatrics, The First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu, PR China.
Li X; Department of Geriatrics, The First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu, PR China.
Tang Q; Department of Geriatrics, The First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu, PR China.
Zhou Y; Department of Geriatrics, The First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu, PR China.

J Cell Physiol ; 236(7): 5399-5410, 2021 07.

Article em En | MEDLINE | ID: mdl-33368224

Assuntos

Tecido Adiposo/metabolismo; Caquexia/metabolismo; Neoplasias Colorretais/complicações; Lipólise/fisiologia; MicroRNAs/metabolismo; Adulto; Idoso; Animais; Caquexia/etiologia; Caquexia/patologia; Neoplasias Colorretais/metabolismo; Neoplasias Colorretais/patologia; Exossomos/metabolismo; Feminino; Proteínas de Homeodomínio/metabolismo; Humanos; Masculino; Camundongos Endogâmicos C57BL; Pessoa de Meia-Idade

Palavras-chave

WAT browning; cancer cachexia; colorectal cancer; exosome

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Caquexia / Neoplasias Colorretais / Tecido Adiposo / MicroRNAs / Lipólise Tipo de estudo: Etiology_studies Limite: Adult / Aged / Animals / Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2021 Tipo de documento: Article

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