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Generation of two human control iPS cell lines (UCLi016-A and UCLi017-A) from healthy donors with no known ocular conditions.
Méjécase, Cécile; Harding, Philippa; Sarkar, Hajrah; Eintracht, Jonathan; Lima Cunha, Dulce; Toualbi, Lyes; Moosajee, Mariya.
Afiliação
  • Méjécase C; UCL Institute of Ophthalmology, London, UK; The Francis Crick Institute, London, UK.
  • Harding P; UCL Institute of Ophthalmology, London, UK.
  • Sarkar H; UCL Institute of Ophthalmology, London, UK; The Francis Crick Institute, London, UK.
  • Eintracht J; UCL Institute of Ophthalmology, London, UK.
  • Lima Cunha D; UCL Institute of Ophthalmology, London, UK.
  • Toualbi L; UCL Institute of Ophthalmology, London, UK; The Francis Crick Institute, London, UK.
  • Moosajee M; UCL Institute of Ophthalmology, London, UK; The Francis Crick Institute, London, UK; Moorfields Eye Hospital NHS Foundation Trust, London, UK; Great Ormond Street Hospital for Children NHS Foundation Trust, London, UK. Electronic address: m.moosajee@ucl.ac.uk.
Stem Cell Res ; 49: 102113, 2020 12.
Article em En | MEDLINE | ID: mdl-33370878
ABSTRACT
Two human induced pluripotent stem cell (hiPSC) lines (UCLi016-A and UCLi017-A) were generated from fibroblast cells of 23- and 34-year-old healthy male donors with no known ocular conditions. Fibroblast cells were derived from skin biopsies and reprogrammed using integration free episomal reprogramming. The established iPSC lines were found to express pluripotency markers, exhibit differentiation potential in vitro and display a normal karyotype. These cell lines will act as a control lines for researchers studying ocular diseases.
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Células-Tronco Pluripotentes Induzidas Limite: Adult / Humans / Male Idioma: En Ano de publicação: 2020 Tipo de documento: Article
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Células-Tronco Pluripotentes Induzidas Limite: Adult / Humans / Male Idioma: En Ano de publicação: 2020 Tipo de documento: Article