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The Hypoglycemic Effect of Berberine and Berberrubine Involves Modulation of Intestinal Farnesoid X Receptor Signaling Pathway and Inhibition of Hepatic Gluconeogenesis.
Sun, Runbin; Kong, Bo; Yang, Na; Cao, Bei; Feng, Dong; Yu, Xiaoyi; Ge, Chun; Feng, Siqi; Fei, Fei; Huang, Jingqiu; Lu, Zhenyao; Xie, Yuan; Yang, Chung S; Guo, Grace L; Wang, Guangji; Aa, Jiye.
Afiliação
  • Sun R; Jiangsu Province Key Laboratory of Drug Metabolism and Pharmacokinetics, State Key Laboratory of Natural Medicines, China Pharmaceutical University, Nanjing, China (R.S., D.F., X.Y., C.G., S.F., J.H., Z.L., Y.X., G.W., J.A.); Department of Pharmacology and Toxicology (B.K., G.L.G.) and Department of
  • Kong B; Jiangsu Province Key Laboratory of Drug Metabolism and Pharmacokinetics, State Key Laboratory of Natural Medicines, China Pharmaceutical University, Nanjing, China (R.S., D.F., X.Y., C.G., S.F., J.H., Z.L., Y.X., G.W., J.A.); Department of Pharmacology and Toxicology (B.K., G.L.G.) and Department of
  • Yang N; Jiangsu Province Key Laboratory of Drug Metabolism and Pharmacokinetics, State Key Laboratory of Natural Medicines, China Pharmaceutical University, Nanjing, China (R.S., D.F., X.Y., C.G., S.F., J.H., Z.L., Y.X., G.W., J.A.); Department of Pharmacology and Toxicology (B.K., G.L.G.) and Department of
  • Cao B; Jiangsu Province Key Laboratory of Drug Metabolism and Pharmacokinetics, State Key Laboratory of Natural Medicines, China Pharmaceutical University, Nanjing, China (R.S., D.F., X.Y., C.G., S.F., J.H., Z.L., Y.X., G.W., J.A.); Department of Pharmacology and Toxicology (B.K., G.L.G.) and Department of
  • Feng D; Jiangsu Province Key Laboratory of Drug Metabolism and Pharmacokinetics, State Key Laboratory of Natural Medicines, China Pharmaceutical University, Nanjing, China (R.S., D.F., X.Y., C.G., S.F., J.H., Z.L., Y.X., G.W., J.A.); Department of Pharmacology and Toxicology (B.K., G.L.G.) and Department of
  • Yu X; Jiangsu Province Key Laboratory of Drug Metabolism and Pharmacokinetics, State Key Laboratory of Natural Medicines, China Pharmaceutical University, Nanjing, China (R.S., D.F., X.Y., C.G., S.F., J.H., Z.L., Y.X., G.W., J.A.); Department of Pharmacology and Toxicology (B.K., G.L.G.) and Department of
  • Ge C; Jiangsu Province Key Laboratory of Drug Metabolism and Pharmacokinetics, State Key Laboratory of Natural Medicines, China Pharmaceutical University, Nanjing, China (R.S., D.F., X.Y., C.G., S.F., J.H., Z.L., Y.X., G.W., J.A.); Department of Pharmacology and Toxicology (B.K., G.L.G.) and Department of
  • Feng S; Jiangsu Province Key Laboratory of Drug Metabolism and Pharmacokinetics, State Key Laboratory of Natural Medicines, China Pharmaceutical University, Nanjing, China (R.S., D.F., X.Y., C.G., S.F., J.H., Z.L., Y.X., G.W., J.A.); Department of Pharmacology and Toxicology (B.K., G.L.G.) and Department of
  • Fei F; Jiangsu Province Key Laboratory of Drug Metabolism and Pharmacokinetics, State Key Laboratory of Natural Medicines, China Pharmaceutical University, Nanjing, China (R.S., D.F., X.Y., C.G., S.F., J.H., Z.L., Y.X., G.W., J.A.); Department of Pharmacology and Toxicology (B.K., G.L.G.) and Department of
  • Huang J; Jiangsu Province Key Laboratory of Drug Metabolism and Pharmacokinetics, State Key Laboratory of Natural Medicines, China Pharmaceutical University, Nanjing, China (R.S., D.F., X.Y., C.G., S.F., J.H., Z.L., Y.X., G.W., J.A.); Department of Pharmacology and Toxicology (B.K., G.L.G.) and Department of
  • Lu Z; Jiangsu Province Key Laboratory of Drug Metabolism and Pharmacokinetics, State Key Laboratory of Natural Medicines, China Pharmaceutical University, Nanjing, China (R.S., D.F., X.Y., C.G., S.F., J.H., Z.L., Y.X., G.W., J.A.); Department of Pharmacology and Toxicology (B.K., G.L.G.) and Department of
  • Xie Y; Jiangsu Province Key Laboratory of Drug Metabolism and Pharmacokinetics, State Key Laboratory of Natural Medicines, China Pharmaceutical University, Nanjing, China (R.S., D.F., X.Y., C.G., S.F., J.H., Z.L., Y.X., G.W., J.A.); Department of Pharmacology and Toxicology (B.K., G.L.G.) and Department of
  • Yang CS; Jiangsu Province Key Laboratory of Drug Metabolism and Pharmacokinetics, State Key Laboratory of Natural Medicines, China Pharmaceutical University, Nanjing, China (R.S., D.F., X.Y., C.G., S.F., J.H., Z.L., Y.X., G.W., J.A.); Department of Pharmacology and Toxicology (B.K., G.L.G.) and Department of
  • Guo GL; Jiangsu Province Key Laboratory of Drug Metabolism and Pharmacokinetics, State Key Laboratory of Natural Medicines, China Pharmaceutical University, Nanjing, China (R.S., D.F., X.Y., C.G., S.F., J.H., Z.L., Y.X., G.W., J.A.); Department of Pharmacology and Toxicology (B.K., G.L.G.) and Department of
  • Wang G; Jiangsu Province Key Laboratory of Drug Metabolism and Pharmacokinetics, State Key Laboratory of Natural Medicines, China Pharmaceutical University, Nanjing, China (R.S., D.F., X.Y., C.G., S.F., J.H., Z.L., Y.X., G.W., J.A.); Department of Pharmacology and Toxicology (B.K., G.L.G.) and Department of
  • Aa J; Jiangsu Province Key Laboratory of Drug Metabolism and Pharmacokinetics, State Key Laboratory of Natural Medicines, China Pharmaceutical University, Nanjing, China (R.S., D.F., X.Y., C.G., S.F., J.H., Z.L., Y.X., G.W., J.A.); Department of Pharmacology and Toxicology (B.K., G.L.G.) and Department of
Drug Metab Dispos ; 49(3): 276-286, 2021 03.
Article em En | MEDLINE | ID: mdl-33376148
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Berberina / Receptores Citoplasmáticos e Nucleares / Gluconeogênese / Hipoglicemiantes / Fígado Limite: Animals Idioma: En Ano de publicação: 2021 Tipo de documento: Article
Texto completo
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Berberina / Receptores Citoplasmáticos e Nucleares / Gluconeogênese / Hipoglicemiantes / Fígado Limite: Animals Idioma: En Ano de publicação: 2021 Tipo de documento: Article