[Sperm-hyaluronan binding assay in in vitro fertilization and embryo transfer].
Zhonghua Nan Ke Xue
; 26(9): 803-806, 2020 Sep.
Article
em Zh
| MEDLINE
| ID: mdl-33377703
ABSTRACT
OBJECTIVE:
To explore the application value of sperm-hyaluronan binding (SHB) assay in in vitro fertilization and embryo transfer (IVF-ET).METHODS:
This retrospective study included 163 cases of IVF-ET performed in our hospital from January to August 2019 due to female fallopian tube abnormality-induced infertility. The men were found with normal seminal parameters at semen analysis. According to the SHB rate, we divided the patients into a normal group (n = 126) and an abnormal group (n = 37) and analyzed the general conditions and the rates of normal fertilization, cleavage, available embryos, embryo implantation and clinical pregnancy.RESULTS:
Statistically significant differences were observed between the normal and abnormal groups in the rates of SHB, normal fertilization and available embryos (P < 0.01 or P < 0.05), but not in the general conditions or the rates of cleavage, embryo implantation and clinical pregnancy.CONCLUSIONS:
The SHB rate is not correlated with sperm concentration or the percentages of progressively motile sperm and morphologically normal sperm. Sperm-hyaluronan binding assay helps predict the outcomes of IVF-ET and embryo quality. An SHB rate of <58.5% indicates low rates of normal fertilization and available embryos, but has no significant correlation with the rates of embryo implantation and clinical pregnancy.Palavras-chave
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Base de dados:
MEDLINE
Assunto principal:
Espermatozoides
/
Fertilização in vitro
/
Transferência Embrionária
/
Ácido Hialurônico
Tipo de estudo:
Observational_studies
/
Prognostic_studies
/
Risk_factors_studies
Limite:
Female
/
Humans
/
Male
/
Pregnancy
Idioma:
Zh
Ano de publicação:
2020
Tipo de documento:
Article