The RNA phosphatase PIR-1 regulates endogenous small RNA pathways in C. elegans.

Chaves, Daniel A; Dai, Hui; Li, Lichao; Moresco, James J; Oh, Myung Eun; Conte, Darryl; Yates, John R; Mello, Craig C; Gu, Weifeng

The RNA phosphatase PIR-1 regulates endogenous small RNA pathways in C. elegans.

Chaves, Daniel A; Dai, Hui; Li, Lichao; Moresco, James J; Oh, Myung Eun; Conte, Darryl; Yates, John R; Mello, Craig C; Gu, Weifeng.

Afiliação

Chaves DA; Department of Molecular Medicine, University of Massachusetts Medical School, Worcester, MA, USA; Faculdade de Medicina, Universidade de Lisboa, Lisboa, Portugal.
Dai H; Department of Molecular, Cell and Systems Biology, University of California, Riverside, Riverside, CA, USA.
Li L; Department of Molecular, Cell and Systems Biology, University of California, Riverside, Riverside, CA, USA.
Moresco JJ; Center for Genetics of Host Defense, UT Southwestern Medical Center, Dallas, TX, USA.
Oh ME; Department of Molecular, Cell and Systems Biology, University of California, Riverside, Riverside, CA, USA.
Conte D; RNA Therapeutics Institute, University of Massachusetts Medical School, Worcester, MA, USA.
Yates JR; Department of Molecular Medicine, Scripps Research Institute, La Jolla, CA, USA.
Mello CC; Department of Molecular Medicine, University of Massachusetts Medical School, Worcester, MA, USA; RNA Therapeutics Institute, University of Massachusetts Medical School, Worcester, MA, USA.
Gu W; Department of Molecular, Cell and Systems Biology, University of California, Riverside, Riverside, CA, USA. Electronic address: weifeng.gu@ucr.edu.

Mol Cell ; 81(3): 546-557.e5, 2021 02 04.

Article em En | MEDLINE | ID: mdl-33378643

Assuntos

Proteínas de Caenorhabditis elegans/metabolismo; Caenorhabditis elegans/enzimologia; Monoéster Fosfórico Hidrolases/metabolismo; Processamento Pós-Transcricional do RNA; RNA/metabolismo; Animais; Animais Geneticamente Modificados; Caenorhabditis elegans/embriologia; Caenorhabditis elegans/genética; Proteínas de Caenorhabditis elegans/genética; Regulação da Expressão Gênica no Desenvolvimento; Monoéster Fosfórico Hidrolases/genética; Fosforilação; RNA/genética; Capuzes de RNA; RNA Polimerase Dependente de RNA/genética; RNA Polimerase Dependente de RNA/metabolismo; Ribonuclease III/genética; Ribonuclease III/metabolismo; Espermatogênese; Especificidade por Substrato

Palavras-chave

RNA binding proteins; RNA phosphatase; RNAi; double-stranded RNAs; embryogenesis; germline gene regulation; germline small RNAs; mRNA regulation; regulation of triphosphorylated RNA; spermatogenesis

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: RNA / Processamento Pós-Transcricional do RNA / Caenorhabditis elegans / Monoéster Fosfórico Hidrolases / Proteínas de Caenorhabditis elegans Limite: Animals Idioma: En Ano de publicação: 2021 Tipo de documento: Article

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