The aryl hydrocarbon receptor and the gut-brain axis.
Cell Mol Immunol
; 18(2): 259-268, 2021 02.
Article
em En
| MEDLINE
| ID: mdl-33408340
ABSTRACT
The aryl hydrocarbon receptor (AHR) is a ligand-activated transcription factor initially identified as the receptor for dioxin. Almost half a century after its discovery, AHR is now recognized as a receptor for multiple physiological ligands, with important roles in health and disease. In this review, we discuss the role of AHR in the gut-brain axis and its potential value as a therapeutic target for immune-mediated diseases.
Palavras-chave
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Doenças Autoimunes
/
Regulação da Expressão Gênica
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Receptores de Hidrocarboneto Arílico
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Eixo Encéfalo-Intestino
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Sistema Imunitário
Tipo de estudo:
Prognostic_studies
Limite:
Animals
/
Humans
Idioma:
En
Ano de publicação:
2021
Tipo de documento:
Article