[Optimal Mono-energy in Mono-energetic Spectral Computed Tomography of Enhanced Renal Cortex in Cortical Phase Based on Iodine Concentration].

ABSTRACT

Objective To identify the optimal mono-energetic enhanced spectral CT for renal cortex in cortical phase based on the iodine concentration. Methods Fifty patients with normal renal function received the abdominal enhanced spectral CT examination.The iodine concentration and CT values of the multiple mono-energetic spectral images were measured on renal cortex in cortical phase,and the correlation between the iodine concentration and the CT values and the coefficient of variation(CV)were analyzed. Results The correlation analysis demonstrated that the correlation coefficient was 0.994,0.994,0.993,0.987,0.976,0.960,and 0.938 between mono-energetic spectral CT images(40-100 keV with interval 10 keV,respectively)and iodine concentration(all P <0.001).The correlation coefficients of 40 keV,50 keV(P=0.007)and 60 keV(P=0.030)were significantly higher compared with that of 70 keV,and the correlation coefficients were not significantly among 40 keV,50 keV and 60 keV(P =0.590).The CV of renal cortex in cortical phase was 0.21,0.20,and 0.19 for 40 keV,50 keV,and 60 keV,respectively. Conclusion 60 keV is the optimal mono-energy for the enhanced spectral CT of the renal cortex in cortical phase.