Biocompatibility and Degradation of a Low Elastic Modulus Ti-35Nb-3Zr Alloy: Nanosurface Engineering for Enhanced Degradation Resistance.
ACS Biomater Sci Eng
; 3(4): 509-517, 2017 Apr 10.
Article
em En
| MEDLINE
| ID: mdl-33429618
ABSTRACT
In this study, the biocompatibility and degradation behavior of a low elastic modulus Ti-35Nb-3Zr alloy were investigated and compared with that of the conventional orthopedic and dental implant materials, i.e., commercially pure titanium (Cp-Ti) and Ti-6Al-4V alloy. The biocompatibility test results suggested that cells proliferate equally well on Ti-35Nb-3Zr and Cp-Ti. The degradation rates of Cp-Ti and Ti-6Al-4V were â¼68% (p < 0.05) and â¼84% (p < 0.05) lower as compared to Ti-35Nb-3Zr, respectively. Interestingly, the passive current density (ipass (1000mv)) of the Ti-35Nb-3Zr alloy was â¼29% lower than that of Cp-Ti, which suggests that the alloying elements in the Ti-35Nb-3Zr alloy have contributed to its passivation behavior. Nanosurface engineering of the Ti-35Nb-3Zr alloy, i.e., a two-step electrochemical process involving anodization (producing nanoporous layer) and calcium phosphate (CaP) deposition, decreased the degradation rate of the alloy by â¼83% (p < 0.05), and notably, it was similar to the conventional Ti-6Al-4V alloy. Hence, it can be suggested that the nanosurface-engineered low elastic modulus Ti-35Nb-3Zr alloy is a promising material for orthopedic and dental implant applications.
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2017
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Article