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Effect of CYP2C19 genotypes on tamoxifen metabolism and early-breast cancer relapse.
Sanchez-Spitman, A B; Swen, J J; Dezentjé, V O; Moes, D J A R; Gelderblom, H; Guchelaar, H J.
Afiliação
  • Sanchez-Spitman AB; Department of Clinical Pharmacy and Toxicology, Leiden University Medical Center, Albinusdreef 2, 2300 RC, Leiden, The Netherlands.
  • Swen JJ; Leiden Network for Personalised Therapeutics, Leiden University Medical Center, Leiden, The Netherlands.
  • Dezentjé VO; Department of Clinical Pharmacy and Toxicology, Leiden University Medical Center, Albinusdreef 2, 2300 RC, Leiden, The Netherlands.
  • Moes DJAR; Leiden Network for Personalised Therapeutics, Leiden University Medical Center, Leiden, The Netherlands.
  • Gelderblom H; Department of Medical Oncology, Netherlands Cancer Institute/Antoni Van Leeuwenhoek, Amsterdam, The Netherlands.
  • Guchelaar HJ; Department of Clinical Pharmacy and Toxicology, Leiden University Medical Center, Albinusdreef 2, 2300 RC, Leiden, The Netherlands.
Sci Rep ; 11(1): 415, 2021 01 11.
Article em En | MEDLINE | ID: mdl-33432065

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Tamoxifeno / Neoplasias da Mama / Inativação Metabólica / Citocromo P-450 CYP2C19 / Recidiva Local de Neoplasia Limite: Aged / Female / Humans / Middle aged Idioma: En Ano de publicação: 2021 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Tamoxifeno / Neoplasias da Mama / Inativação Metabólica / Citocromo P-450 CYP2C19 / Recidiva Local de Neoplasia Limite: Aged / Female / Humans / Middle aged Idioma: En Ano de publicação: 2021 Tipo de documento: Article