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Antagonizing somatostatin receptor subtype 2 and 5 reduces blood glucose in a gut- and GLP-1R-dependent manner.
Jepsen, Sara L; Albrechtsen, Nicolai J Wewer; Windeløv, Johanne A; Galsgaard, Katrine D; Hunt, Jenna E; Farb, Thomas B; Kissow, Hannelouise; Pedersen, Jens; Deacon, Carolyn F; Martin, Rainer E; Holst, Jens J.
Afiliação
  • Jepsen SL; Department of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
  • Albrechtsen NJW; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
  • Windeløv JA; Department of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
  • Galsgaard KD; Novo Nordisk Foundation Center for Protein Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
  • Hunt JE; Department of Clinical Biochemistry, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark.
  • Farb TB; Department of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
  • Kissow H; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
  • Pedersen J; Department of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
  • Deacon CF; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
  • Martin RE; Department of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
  • Holst JJ; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
JCI Insight ; 6(4)2021 02 22.
Article em En | MEDLINE | ID: mdl-33434183
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Glicemia / Receptores de Somatostatina / Receptor do Peptídeo Semelhante ao Glucagon 1 / Hipoglicemiantes Limite: Animals Idioma: En Ano de publicação: 2021 Tipo de documento: Article
Texto completo
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PubMed Links
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Glicemia / Receptores de Somatostatina / Receptor do Peptídeo Semelhante ao Glucagon 1 / Hipoglicemiantes Limite: Animals Idioma: En Ano de publicação: 2021 Tipo de documento: Article