Immune Escape in Prostate Cancer: Known and Predicted Mechanisms and Targets.
Urol Clin North Am
; 47(4S): e9-e16, 2020 Nov.
Article
em En
| MEDLINE
| ID: mdl-33446324
Complex immune evasion mechanisms and lack of biomarkers predicting responsiveness to immune checkpoint blockade therapies compromise immunotherapy's therapeutic efficacy for patients with prostate cancer. The authors review established and nominated immune evasion mechanisms in prostate cancer and discuss how the precise treatment strategies can be developed to improve efficacy of immunotherapy.
Palavras-chave
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Neoplasias da Próstata
/
Interferon gama
/
Evasão Tumoral
/
Inibidores de Checkpoint Imunológico
Tipo de estudo:
Prognostic_studies
/
Risk_factors_studies
Limite:
Humans
/
Male
Idioma:
En
Ano de publicação:
2020
Tipo de documento:
Article