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Design, synthesis, biological evaluation of 3,5-diaryl-4,5-dihydro-1H-pyrazole carbaldehydes as non-purine xanthine oxidase inhibitors: Tracing the anticancer mechanism via xanthine oxidase inhibition.
Joshi, Gaurav; Sharma, Manisha; Kalra, Sourav; Gavande, Navnath S; Singh, Sandeep; Kumar, Raj.
Afiliação
  • Joshi G; Laboratory for Drug Design and Synthesis, Department of Pharmaceutical Sciences and Natural Products, School of Health Sciences, Central University of Punjab, Bathinda 151 001, India.
  • Sharma M; Laboratory for Drug Design and Synthesis, Department of Pharmaceutical Sciences and Natural Products, School of Health Sciences, Central University of Punjab, Bathinda 151 001, India.
  • Kalra S; Department of Human Genetics and Molecular Medicine, Central University of Punjab, Bathinda 151 001, India.
  • Gavande NS; Department of Pharmaceutical Sciences, Wayne State University College of Pharmacy and Health Sciences, Detroit, MI 48201, USA. Electronic address: ngavande@wayne.edu.
  • Singh S; Department of Human Genetics and Molecular Medicine, Central University of Punjab, Bathinda 151 001, India. Electronic address: sandeepsingh82@gmail.com.
  • Kumar R; Laboratory for Drug Design and Synthesis, Department of Pharmaceutical Sciences and Natural Products, School of Health Sciences, Central University of Punjab, Bathinda 151 001, India. Electronic address: raj.khunger@cup.edu.in.
Bioorg Chem ; 107: 104620, 2021 02.
Article em En | MEDLINE | ID: mdl-33454509
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Pirazóis / Xantina Oxidase / Desenho de Fármacos / Inibidores Enzimáticos Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Pirazóis / Xantina Oxidase / Desenho de Fármacos / Inibidores Enzimáticos Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article