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Smad3 deficiency promotes beta cell proliferation and function in db/db mice via restoring Pax6 expression.
Sheng, Jingyi; Wang, Li; Tang, Patrick Ming-Kuen; Wang, Hong-Lian; Li, Jian-Chun; Xu, Bi-Hua; Xue, Vivian Weiwen; Tan, Rui-Zhi; Jin, Nana; Chan, Ting-Fung; Huang, Xiao-Ru; Ma, Ronald Cw; Lan, Hui-Yao.
Afiliação
  • Sheng J; Department of Medicine and Therapeutics, Li Ka Shing Institute of Health Sciences, The Chinese University of Hong Kong.
  • Wang L; State Key Laboratory of Bioelectronics, Jiangsu Key Laboratory for Biomaterials and Devices, School of Biological Sciences & Medical Engineering, Southeast University, Nanjing, China.
  • Tang PM; Department of Medicine and Therapeutics, Li Ka Shing Institute of Health Sciences, The Chinese University of Hong Kong.
  • Wang HL; Research Center for Integrated Chinese and Western Medicine, and Department of Cardiology, The Second Affiliated Hospital, Southwest Medical University, Luzhou, Sichuan, China.
  • Li JC; Department of Medicine and Therapeutics, Li Ka Shing Institute of Health Sciences, The Chinese University of Hong Kong.
  • Xu BH; Department of Anatomical and Cellular Pathology, State Key Laboratory of Translational Oncology, The Chinese University of Hong Kong.
  • Xue VW; Department of Medicine and Therapeutics, Li Ka Shing Institute of Health Sciences, The Chinese University of Hong Kong.
  • Tan RZ; Research Center for Integrated Chinese and Western Medicine, and Department of Cardiology, The Second Affiliated Hospital, Southwest Medical University, Luzhou, Sichuan, China.
  • Jin N; Department of Medicine and Therapeutics, Li Ka Shing Institute of Health Sciences, The Chinese University of Hong Kong.
  • Chan TF; Research Center for Integrated Chinese and Western Medicine, and Department of Cardiology, The Second Affiliated Hospital, Southwest Medical University, Luzhou, Sichuan, China.
  • Huang XR; Department of Medicine and Therapeutics, Li Ka Shing Institute of Health Sciences, The Chinese University of Hong Kong.
  • Ma RC; Department of Anatomical and Cellular Pathology, State Key Laboratory of Translational Oncology, The Chinese University of Hong Kong.
  • Lan HY; Department of Medicine and Therapeutics, Li Ka Shing Institute of Health Sciences, The Chinese University of Hong Kong.
Theranostics ; 11(6): 2845-2859, 2021.
Article em En | MEDLINE | ID: mdl-33456576

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Ilhotas Pancreáticas / Proliferação de Células / Diabetes Mellitus Experimental / Células Secretoras de Insulina / Proteína Smad3 / Fator de Transcrição PAX6 Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Ano de publicação: 2021 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Ilhotas Pancreáticas / Proliferação de Células / Diabetes Mellitus Experimental / Células Secretoras de Insulina / Proteína Smad3 / Fator de Transcrição PAX6 Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Ano de publicação: 2021 Tipo de documento: Article