HIV Protein Tat Induces Macrophage Dysfunction and Atherosclerosis Development in Low-Density Lipoprotein Receptor-Deficient Mice.

Meng, Zhaojie; Hernandez, Rebecca; Liu, Jingwei; Gwag, Taesik; Lu, Weiwei; Hsiai, Tzung K; Kaul, Marcus; Zhou, Tong; Zhou, Changcheng

Meng, Zhaojie; Hernandez, Rebecca; Liu, Jingwei; Gwag, Taesik; Lu, Weiwei; Hsiai, Tzung K; Kaul, Marcus; Zhou, Tong; Zhou, Changcheng.

Afiliação

Meng Z; Division of Biomedical Sciences, School of Medicine, University of California, Riverside, CA, USA.
Hernandez R; Division of Biomedical Sciences, School of Medicine, University of California, Riverside, CA, USA.
Liu J; Division of Biomedical Sciences, School of Medicine, University of California, Riverside, CA, USA.
Gwag T; Department of Pharmacology and Nutritional Sciences, College of Medicine, University of Kentucky, Lexington, KY, USA.
Lu W; Department of Pharmacology and Nutritional Sciences, College of Medicine, University of Kentucky, Lexington, KY, USA.
Hsiai TK; Departments of Medicine and Bioengineering, David Geffen School of Medicine, Henry Samueli School of Engineering and Applied Science, University of California, Los Angeles, CA, USA.
Kaul M; Division of Biomedical Sciences, School of Medicine, University of California, Riverside, CA, USA.
Zhou T; Department of Physiology and Cell Biology, Reno School of Medicine, University of Nevada, Reno, NV, USA.
Zhou C; Division of Biomedical Sciences, School of Medicine, University of California, Riverside, CA, USA. changcheng.zhou@ucr.edu.

Cardiovasc Drugs Ther ; 36(2): 201-215, 2022 04.

Article em En | MEDLINE | ID: mdl-33459922

Assuntos

Aterosclerose; Infecções por HIV; Animais; Aterosclerose/metabolismo; Infecções por HIV/complicações; Infecções por HIV/metabolismo; Infecções por HIV/patologia; Quinase I-kappa B/genética; Quinase I-kappa B/metabolismo; Inflamação/metabolismo; Lipoproteínas LDL; Macrófagos/metabolismo; Camundongos; Camundongos Endogâmicos C57BL; Camundongos Knockout; NF-kappa B/metabolismo; Proteínas Serina-Treonina Quinases; Receptores de LDL/metabolismo

Palavras-chave

Atherosclerosis; HIV infection; Inflammation; IκB kinase ß; Macrophages; Nuclear factor-κB

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Infecções por HIV / Aterosclerose Limite: Animals Idioma: En Ano de publicação: 2022 Tipo de documento: Article

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