Longevity pathways in stress resistance: targeting NAD and sirtuins to treat the pathophysiology of hemorrhagic shock.

Sims, Carrie A; Labiner, Hanna E; Shah, Sohini S; Baur, Joseph A

Sims, Carrie A; Labiner, Hanna E; Shah, Sohini S; Baur, Joseph A.

Afiliação

Sims CA; Division of Trauma, Critical Care, and Burn at The Ohio State University Wexner Medical Center, The Ohio State University, Faculty Office Tower, 395 12th Ave, Room 654, Columbus, OH, 43210, USA. Carrie.Sims@osumc.edu.
Labiner HE; Division of Trauma, Critical Care, and Burn at The Ohio State University Wexner Medical Center, The Ohio State University, Faculty Office Tower, 395 12th Ave, Room 654, Columbus, OH, 43210, USA.
Shah SS; Institute for Diabetes, Obesity and Metabolism and Department of Physiology, Perelman School of Medicine, University of Pennsylvania, 3400 Civic Center Blvd., SCTR 12-114, Philadelphia, PA, 19104, USA.
Baur JA; Institute for Diabetes, Obesity and Metabolism and Department of Physiology, Perelman School of Medicine, University of Pennsylvania, 3400 Civic Center Blvd., SCTR 12-114, Philadelphia, PA, 19104, USA. baur@mail.med.upenn.edu.

Geroscience ; 43(3): 1217-1228, 2021 06.

Article em En | MEDLINE | ID: mdl-33462707

Assuntos

Choque Hemorrágico; Sirtuínas; Estilbenos; Animais; Longevidade; Camundongos; NAD; Ratos; Choque Hemorrágico/tratamento farmacológico

Palavras-chave

Aging; Hemorrhagic shock; Mononucleotide; NAD; Nicotinamide; Resveratrol; Riboside; SIRT1; Sirtuins; Stress

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Choque Hemorrágico / Estilbenos / Sirtuínas Limite: Animals Idioma: En Ano de publicação: 2021 Tipo de documento: Article

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