Long-term effects on bone mineral density after four years of treatment with two intensive combination strategies, including initially high-dose prednisolone, in early rheumatoid arthritis patients: the COBRA-light trial.

Lucassen, M J J; Ter Wee, M M; den Uyl, D; Konijn, N P C; Nurmohamed, M T; Voskuyl, A E; van Schaardenburg, D; Kerstens, P J S M; Bultink, I E M; Boers, M; Lems, W F

Lucassen, M J J; Ter Wee, M M; den Uyl, D; Konijn, N P C; Nurmohamed, M T; Voskuyl, A E; van Schaardenburg, D; Kerstens, P J S M; Bultink, I E M; Boers, M; Lems, W F.

Afiliação

Lucassen MJJ; Department of Epidemiology and Data Science, Amsterdam UMC, VU University Amsterdam, De Boelelaan 1089a, 1081 HV, Amsterdam, The Netherlands.
Ter Wee MM; Department of Rheumatology and Clinical Immunology, Amsterdam Rheumatology and immunology Center, Amsterdam UMC, VU University Amsterdam, De Boelelaan, 1117, Amsterdam, Netherlands.
den Uyl D; Department of Epidemiology and Data Science, Amsterdam UMC, VU University Amsterdam, De Boelelaan 1089a, 1081 HV, Amsterdam, The Netherlands. m.terwee@amsterdamumc.nl.
Konijn NPC; Department of Rheumatology and Clinical Immunology, Amsterdam Rheumatology and immunology Center, Amsterdam UMC, VU University Amsterdam, De Boelelaan, 1117, Amsterdam, Netherlands. m.terwee@amsterdamumc.nl.
Nurmohamed MT; Department of Rheumatology and Clinical Immunology, Amsterdam Rheumatology and immunology Center, Amsterdam UMC, VU University Amsterdam, De Boelelaan, 1117, Amsterdam, Netherlands.
Voskuyl AE; Department of Rheumatology and Clinical Immunology, Amsterdam Rheumatology and immunology Center, Amsterdam UMC, VU University Amsterdam, De Boelelaan, 1117, Amsterdam, Netherlands.
van Schaardenburg D; Department of Rheumatology and Clinical Immunology, Amsterdam Rheumatology and immunology Center, Amsterdam UMC, VU University Amsterdam, De Boelelaan, 1117, Amsterdam, Netherlands.
Kerstens PJSM; Amsterdam Rheumatology and immunology Center, location Reade Rheumatology and Rehabilitation Center, Amsterdam, Netherlands.
Bultink IEM; Department of Rheumatology and Clinical Immunology, Amsterdam Rheumatology and immunology Center, Amsterdam UMC, VU University Amsterdam, De Boelelaan, 1117, Amsterdam, Netherlands.
Boers M; Amsterdam Rheumatology and immunology Center, location Reade Rheumatology and Rehabilitation Center, Amsterdam, Netherlands.
Lems WF; Department of Rheumatology and Clinical Immunology, Amsterdam Rheumatology and immunology Center, Amsterdam UMC, University of Amsterdam, Meibergdreef 9, Amsterdam, Netherlands.

Osteoporos Int ; 32(7): 1441-1449, 2021 Jul.

Article em En | MEDLINE | ID: mdl-33464392

Assuntos

Antirreumáticos; Artrite Reumatoide; Absorciometria de Fóton; Antirreumáticos/efeitos adversos; Artrite Reumatoide/tratamento farmacológico; Densidade Óssea; Quimioterapia Combinada; Feminino; Humanos; Masculino; Metotrexato/uso terapêutico; Pessoa de Meia-Idade; Prednisolona/efeitos adversos

Palavras-chave

Bone mineral density; COBRA-light; Combination therapy; Early RA; Rheumatoid arthritis

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Artrite Reumatoide / Antirreumáticos Tipo de estudo: Clinical_trials Limite: Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2021 Tipo de documento: Article

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