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Skeletal Maturation in the Current Pediatric Mexican Population.
Klünder-Klünder, Miguel; Espinosa-Espindola, Montserrat; Lopez-Gonzalez, Desiree; Loyo, Mariana Sánchez-Curiel; Suárez, Pilar Dies; Miranda-Lora, América Liliana.
Afiliação
  • Klünder-Klünder M; Deputy Director of Research, Hospital Infantil de México Federico Gómez, Mexico City, Mexico.
  • Espinosa-Espindola M; Endocrinological and Nutritional Epidemiology Research Unit, Universidad Nacional Autónoma de México and Hospital Infantil de México Federico Gómez, Mexico City, Mexico.
  • Lopez-Gonzalez D; Clinical Epidemiology Research Unit, Hospital Infantil de México Federico Gómez, Mexico City, Mexico.
  • Loyo MS; Radiology Department, Hospital Infantil de México Federico Gómez, Mexico City, Mexico.
  • Suárez PD; Radiology Department, Hospital Infantil de México Federico Gómez, Mexico City, Mexico.
  • Miranda-Lora AL; Endocrinological and Nutritional Epidemiology Research Unit, Universidad Nacional Autónoma de México and Hospital Infantil de México Federico Gómez, Mexico City, Mexico. Electronic address: americaml@hotmail.com.
Endocr Pract ; 26(10): 1053-1061, 2020 Oct.
Article em En | MEDLINE | ID: mdl-33471706
OBJECTIVE: The most commonly used methods for bone age (BA) reading were described in the Caucasian population decades ago. However, there are secular trends in skeletal maturation and different BA patterns between ethnic groups. Automated BA reading makes updating references easier and more precise than human reading. The objective of the present study was to present automated BA reference curves according to chronological age and gender in the Mexican population and compare the maturation tempo with that of other populations. METHODS: The study included 923 healthy participants aged 5 to 18 years between 2017 and 2018. A hand radio-graph was analyzed using BoneXpert software to obtain the automated BA reading according to Greulich and Pyle (G&P) and Tanner-Whitehouse 2 (TW2) references. We constructed reference curves using the average difference between the BA and chronological age according to sex and age. RESULTS: The G&P and TW2 automated reference curves showed that Mexican boys exhibit delays in BA during middle childhood by 0.5 to 0.7 (95% confidence interval [CI], -0.9 to -0.2) years; however, they demonstrate an advanced BA of up to 1.1 (95% CI, 0.8 to 1.4) years at the end of puberty. Mexican girls exhibited a delay in BA by 0.3 to 0.6 (95% CI, -0.9 to -0.1) years before puberty and an advanced BA of up to 0.9 (95% CI, 0.7 to 1.2) years at the end of puberty. CONCLUSION: Mexican children aged <10 years exhibited a delay in skeletal maturity, followed by an advanced BA by approximately 1 year at the end of puberty. This may affect the estimation of growth potential in this population.
Assuntos

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Determinação da Idade pelo Esqueleto / Mãos Limite: Adolescent / Child / Child, preschool / Female / Humans / Male País como assunto: Mexico Idioma: En Ano de publicação: 2020 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Determinação da Idade pelo Esqueleto / Mãos Limite: Adolescent / Child / Child, preschool / Female / Humans / Male País como assunto: Mexico Idioma: En Ano de publicação: 2020 Tipo de documento: Article