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Interplay of Aging and Lot-to-Lot Variability on the Physical and Chemical Properties of Excipients: A Case Study of Mono- and Diglycerides.
Kushwah, Varun; Saraf, Isha; Yeoh, Thean; Ardelean, Ioan; Weber, Hansjoerg; Sarkar, Avik; Chen, Raymond; Vogel, Trevor; Modhave, Dattatray; Laggner, Peter; Paudel, Amrit.
Afiliação
  • Kushwah V; Research Center Pharmaceutical Engineering (RCPE) GmbH, Inffeldgasse 13, 8010 Graz, Austria.
  • Saraf I; Research Center Pharmaceutical Engineering (RCPE) GmbH, Inffeldgasse 13, 8010 Graz, Austria.
  • Yeoh T; Drug Product Design, Worldwide Research, Development and Medical, Pfizer Inc., Groton, Connecticut 06340, United States.
  • Ardelean I; Department of Physics and Chemistry, Technical University of Cluj-Napoca, Cluj-Napoca 400084, Romania.
  • Weber H; Institute of Organic Chemistry, Graz University of Technology, Stremayrgasse 9A, 8010 Graz, Austria.
  • Sarkar A; Drug Product Design, Worldwide Research, Development and Medical, Pfizer Inc., Groton, Connecticut 06340, United States.
  • Chen R; Analytical R&D, Worldwide Research, Development and Medical, Pfizer Inc., Groton, Connecticut 06340, United States.
  • Vogel T; Drug Product Design, Worldwide Research, Development and Medical, Pfizer Inc., Groton, Connecticut 06340, United States.
  • Modhave D; Research Center Pharmaceutical Engineering (RCPE) GmbH, Inffeldgasse 13, 8010 Graz, Austria.
  • Laggner P; Research Center Pharmaceutical Engineering (RCPE) GmbH, Inffeldgasse 13, 8010 Graz, Austria.
  • Paudel A; Research Center Pharmaceutical Engineering (RCPE) GmbH, Inffeldgasse 13, 8010 Graz, Austria.
Mol Pharm ; 18(3): 862-877, 2021 03 01.
Article em En | MEDLINE | ID: mdl-33475378

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Diglicerídeos / Excipientes Idioma: En Ano de publicação: 2021 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Diglicerídeos / Excipientes Idioma: En Ano de publicação: 2021 Tipo de documento: Article