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GATA2 regulates mast cell identity and responsiveness to antigenic stimulation by promoting chromatin remodeling at super-enhancers.
Li, Yapeng; Gao, Junfeng; Kamran, Mohammad; Harmacek, Laura; Danhorn, Thomas; Leach, Sonia M; O'Connor, Brian P; Hagman, James R; Huang, Hua.
Afiliação
  • Li Y; Department of Immunology and Genomic Medicine, National Jewish Health, Denver, CO, 80206, USA.
  • Gao J; Department of Immunology and Genomic Medicine, National Jewish Health, Denver, CO, 80206, USA.
  • Kamran M; Department of Immunology and Genomic Medicine, National Jewish Health, Denver, CO, 80206, USA.
  • Harmacek L; Center for Genes, Environment and Health, National Jewish Health, Denver, CO, 80206, USA.
  • Danhorn T; Center for Genes, Environment and Health, National Jewish Health, Denver, CO, 80206, USA.
  • Leach SM; Department of Immunology and Genomic Medicine, National Jewish Health, Denver, CO, 80206, USA.
  • O'Connor BP; Center for Genes, Environment and Health, National Jewish Health, Denver, CO, 80206, USA.
  • Hagman JR; Center for Genes, Environment and Health, National Jewish Health, Denver, CO, 80206, USA.
  • Huang H; Department of Immunology and Genomic Medicine, National Jewish Health, Denver, CO, 80206, USA.
Nat Commun ; 12(1): 494, 2021 01 21.
Article em En | MEDLINE | ID: mdl-33479210

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Elementos Facilitadores Genéticos / Montagem e Desmontagem da Cromatina / Fator de Transcrição GATA2 / Mastócitos / Antígenos Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Ano de publicação: 2021 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Elementos Facilitadores Genéticos / Montagem e Desmontagem da Cromatina / Fator de Transcrição GATA2 / Mastócitos / Antígenos Tipo de estudo: Prognostic_studies Limite: Animals Idioma: En Ano de publicação: 2021 Tipo de documento: Article