Adjunctive Statin Therapy Reduces Mortality After Acute Hemorrhagic Stroke.

Lin, Cheng-Kai; Chen, Po-Yuan; Wu, Yu-Ying; Wu, Cheng-Chun; Chen, Han-Jung; Liang, Cheng-Loong; Lee, Yi-Che; Lin, Chi-Wei; Hung, Chao-Ming; Wang, Hao-Kuang

Lin, Cheng-Kai; Chen, Po-Yuan; Wu, Yu-Ying; Wu, Cheng-Chun; Chen, Han-Jung; Liang, Cheng-Loong; Lee, Yi-Che; Lin, Chi-Wei; Hung, Chao-Ming; Wang, Hao-Kuang.

Afiliação

Lin CK; School of Medicine, College of Medicine, I-Shou University, Kaohsiung, Taiwan.
Chen PY; Department of Neurosurgery, E-Da Hospital, Kaohsiung, Taiwan.
Wu YY; School of Medicine, College of Medicine, I-Shou University, Kaohsiung, Taiwan.
Wu CC; Department of Neurosurgery, E-Da Hospital, Kaohsiung, Taiwan.
Chen HJ; School of Medicine, College of Medicine, I-Shou University, Kaohsiung, Taiwan.
Liang CL; Department of Neurosurgery, E-Da Hospital, Kaohsiung, Taiwan.
Lee YC; School of Medicine, College of Medicine, I-Shou University, Kaohsiung, Taiwan.
Lin CW; School of Medicine, College of Medicine, I-Shou University, Kaohsiung, Taiwan.
Hung CM; Department of Neurosurgery, E-Da Hospital, Kaohsiung, Taiwan.
Wang HK; School of Medicine, College of Medicine, I-Shou University, Kaohsiung, Taiwan.

Risk Manag Healthc Policy ; 14: 177-183, 2021.

Article em En | MEDLINE | ID: mdl-33488130

ABSTRACT

ABSTRACT

BACKGROUND:

Statin treatment improves clinical outcomes in patients with ischemic strokes, although there is no evidence regarding the safety of statin therapy in patients with intracerebral hemorrhage (ICH). This study aimed at evaluating the effects of continuing statin treatment after ICH.

METHODS:

Data were obtained from the National Health Insurance Research Database in Taiwan. We retrospectively compared the data of patients with and without statin exposure after ICH. The outcomes of interest were recurrence of hemorrhagic stroke and mortality during a follow-up period of 10 years.

RESULTS:

During the 10-year follow-up period, the mortality rate was 32.73% in the statin group and 42.77% in the non-statin group. Statin therapy in patients with acute ICH with dyslipidemia can decrease mortality.