Centrosomes: Please keep your social distance!
EMBO J
; 40(4): e107525, 2021 02 15.
Article
em En
| MEDLINE
| ID: mdl-33491191
ABSTRACT
Accurate control of centrosome number is essential for proper chromosome segregation, and it is well established that centrosome abnormalities can trigger a p53-dependent cell cycle arrest. Two new studies published in The EMBO Journal demonstrate how PIDD1 is recruited to centrosomes and that the localization of PIDD1 to distal appendages of centrosomes is required for PIDDosome activation at clustered supernumerary centrosomes.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Centrossomo
/
Segregação de Cromossomos
Idioma:
En
Ano de publicação:
2021
Tipo de documento:
Article