Your browser doesn't support javascript.
loading
Corneal angiogenic privilege and its failure.
Di Zazzo, Antonio; Gaudenzi, Daniele; Yin, Jia; Coassin, Marco; Fernandes, Merle; Dana, Reza; Bonini, Stefano.
Afiliação
  • Di Zazzo A; Ophthalmology Operative Complex Unit, University Campus Bio-Medico, Rome, Italy. Electronic address: a.dizazzo@unicampus.it.
  • Gaudenzi D; Ophthalmology Operative Complex Unit, University Campus Bio-Medico, Rome, Italy.
  • Yin J; Massachusetts Eye and Ear, Department of Ophthalmology, Harvard Medical School, Boston, MA, USA.
  • Coassin M; Ophthalmology Operative Complex Unit, University Campus Bio-Medico, Rome, Italy.
  • Fernandes M; Cornea and Anterior Segment Services, LV Prasad Eye Institute, GMR Varalakshmi Campus, Visakhapatnam, India.
  • Dana R; Massachusetts Eye and Ear, Department of Ophthalmology, Harvard Medical School, Boston, MA, USA.
  • Bonini S; Ophthalmology Operative Complex Unit, University Campus Bio-Medico, Rome, Italy.
Exp Eye Res ; 204: 108457, 2021 03.
Article em En | MEDLINE | ID: mdl-33493471
The cornea actively maintains its own avascular status to preserve its ultimate optical function. This corneal avascular state is also defined as "corneal angiogenic privilege", which results from a critical and sensitive balance between anti-angiogenic and pro-angiogenic mechanisms. In our review, we aim to explore the complex equilibrium among multiple mediators which prevents neovascularization in the resting cornea, as well as to unveil the evolutive process which leads to corneal angiogenesis in response to different injuries.
Assuntos

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neovascularização da Córnea / Córnea Limite: Animals / Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neovascularização da Córnea / Córnea Limite: Animals / Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article