Catalase deficiency induces reactive oxygen species mediated pexophagy and cell death in the liver during prolonged fasting.

Dutta, Raghbendra Kumar; Maharjan, Yunash; Lee, Joon No; Park, Channy; Ho, Ye-Shih; Park, Raekil

Dutta, Raghbendra Kumar; Maharjan, Yunash; Lee, Joon No; Park, Channy; Ho, Ye-Shih; Park, Raekil.

Afiliação

Dutta RK; Department of Biomedical Science & Engineering, Gwangju Institute of Science & Technology, Gwangju, Republic of Korea.
Maharjan Y; Department of Biomedical Science & Engineering, Gwangju Institute of Science & Technology, Gwangju, Republic of Korea.
Lee JN; Department of Biomedical Science & Engineering, Gwangju Institute of Science & Technology, Gwangju, Republic of Korea.
Park C; Department of Biomedical Science & Engineering, Gwangju Institute of Science & Technology, Gwangju, Republic of Korea.
Ho YS; Institute of Environmental Health Sciences and Department of Biochemistry and Molecular Biology, Wayne State University, Detroit, Michigan, USA.
Park R; Department of Biomedical Science & Engineering, Gwangju Institute of Science & Technology, Gwangju, Republic of Korea.

Biofactors ; 47(1): 112-125, 2021 Jan.

Article em En | MEDLINE | ID: mdl-33496364

Assuntos

Catalase/fisiologia; Fígado/patologia; Macroautofagia; Peroxissomos; Espécies Reativas de Oxigênio/metabolismo; Acetilcisteína/uso terapêutico; Animais; Catalase/genética; Células Cultivadas; Privação de Alimentos; Hepatite/tratamento farmacológico; Hepatite/etiologia; Hepatite/metabolismo; Hepatite/patologia; Fígado/metabolismo; Camundongos Knockout

Palavras-chave

catalase; cell death; liver; pexophagy; reactive oxygen species

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Catalase / Espécies Reativas de Oxigênio / Peroxissomos / Macroautofagia / Fígado Tipo de estudo: Etiology_studies Limite: Animals Idioma: En Ano de publicação: 2021 Tipo de documento: Article

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