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Repurposing the orphan drug nitisinone to control the transmission of African trypanosomiasis.
Sterkel, Marcos; Haines, Lee R; Casas-Sánchez, Aitor; Owino Adung'a, Vincent; Vionette-Amaral, Raquel J; Quek, Shannon; Rose, Clair; Silva Dos Santos, Mariana; García Escude, Natalia; Ismail, Hanafy M; Paine, Mark I; Barribeau, Seth M; Wagstaff, Simon; MacRae, James I; Masiga, Daniel; Yakob, Laith; Oliveira, Pedro L; Acosta-Serrano, Álvaro.
Afiliação
  • Sterkel M; Centro Regional de Estudios Genómicos, Facultad de Ciencias Exactas, Universidad Nacional de La Plata, Argentina.
  • Haines LR; Department of Vector Biology, Liverpool School of Tropical Medicine, United Kingdom.
  • Casas-Sánchez A; Department of Vector Biology, Liverpool School of Tropical Medicine, United Kingdom.
  • Owino Adung'a V; International Centre of Insect Physiology and Ecology, Nairobi, Kenya.
  • Vionette-Amaral RJ; Department of Biochemistry and Molecular Biology, Egerton University, Kenya.
  • Quek S; Department of Vector Biology, Liverpool School of Tropical Medicine, United Kingdom.
  • Rose C; Department of Tropical Disease Biology, Liverpool School of Tropical Medicine, United Kingdom.
  • Silva Dos Santos M; Department of Vector Biology, Liverpool School of Tropical Medicine, United Kingdom.
  • García Escude N; Crick Institute, London, United Kingdom.
  • Ismail HM; Department of Vector Biology, Liverpool School of Tropical Medicine, United Kingdom.
  • Paine MI; Department of Vector Biology, Liverpool School of Tropical Medicine, United Kingdom.
  • Barribeau SM; Department of Vector Biology, Liverpool School of Tropical Medicine, United Kingdom.
  • Wagstaff S; Department of Ecology Evolution & Behaviour, Institute of Integrative Biology, University of Liverpool, United Kingdom.
  • MacRae JI; Department of Tropical Disease Biology, Liverpool School of Tropical Medicine, United Kingdom.
  • Masiga D; Crick Institute, London, United Kingdom.
  • Yakob L; International Centre of Insect Physiology and Ecology, Nairobi, Kenya.
  • Oliveira PL; Department of Disease Control, London School of Hygiene and Tropical Medicine, United Kingdom.
  • Acosta-Serrano Á; Instituto de Bioquímica Médica Leopoldo de Meis, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil.
PLoS Biol ; 19(1): e3000796, 2021 01.
Article em En | MEDLINE | ID: mdl-33497373
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Tripanossomíase Africana / Controle de Infecções / Cicloexanonas / Reposicionamento de Medicamentos / Nitrobenzoatos Limite: Animals / Female / Humans / Male Idioma: En Ano de publicação: 2021 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Tripanossomíase Africana / Controle de Infecções / Cicloexanonas / Reposicionamento de Medicamentos / Nitrobenzoatos Limite: Animals / Female / Humans / Male Idioma: En Ano de publicação: 2021 Tipo de documento: Article