The KATP channel opener, nicorandil, ameliorates brain damage by modulating synaptogenesis after ischemic stroke.

Zhao, Yuanzheng; Yang, Zhuoying; He, Yuanhong; Sun, Ruonan; Yuan, Heping

Zhao, Yuanzheng; Yang, Zhuoying; He, Yuanhong; Sun, Ruonan; Yuan, Heping.

Afiliação

Zhao Y; Department of Neurology, The Fifth Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, China.
Yang Z; Department of Neurology, The Fifth Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, China.
He Y; Department of Neurology, The Fifth Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, China.
Sun R; Department of Neurology, The Fifth Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, China.
Yuan H; Department of Neurology, The Fifth Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, China.

PLoS One ; 16(1): e0246019, 2021.

Article em En | MEDLINE | ID: mdl-33497397

Assuntos

AVC Isquêmico/tratamento farmacológico; Canais KATP/metabolismo; Fármacos Neuroprotetores/uso terapêutico; Nicorandil/uso terapêutico; Sinapses/efeitos dos fármacos; Vasodilatadores/uso terapêutico; Animais; Circulação Cerebrovascular/efeitos dos fármacos; AVC Isquêmico/metabolismo; AVC Isquêmico/patologia; Fármacos Neuroprotetores/farmacologia; Nicorandil/farmacologia; Ratos; Ratos Sprague-Dawley; Sinapses/metabolismo; Sinapses/patologia; Vasodilatadores/farmacologia

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Sinapses / Vasodilatadores / Fármacos Neuroprotetores / Nicorandil / Canais KATP / AVC Isquêmico Limite: Animals Idioma: En Ano de publicação: 2021 Tipo de documento: Article

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