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Atorvastatin impairs liver mitochondrial function in obese Göttingen Minipigs but heart and skeletal muscle are not affected.
Christiansen, Liselotte Bruun; Dohlmann, Tine Lovsø; Ludvigsen, Trine Pagh; Parfieniuk, Ewa; Ciborowski, Michal; Szczerbinski, Lukasz; Kretowski, Adam; Desler, Claus; Tiano, Luca; Orlando, Patrick; Martinussen, Torben; Olsen, Lisbeth Høier; Larsen, Steen.
Afiliação
  • Christiansen LB; The LIFEPHARM Centre, Department of Veterinary and Animal Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Ridebanevej 9, 1870, Frederiksberg, Denmark. lbc@sund.ku.dk.
  • Dohlmann TL; Xlab, Center for Healthy Aging, Department of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Blegdamsvej 3B, 2200, Copenhagen, Denmark.
  • Ludvigsen TP; Global Drug Development, Novo Nordisk A/S, Novo Nordisk Park, 2760, Måløv, Denmark.
  • Parfieniuk E; Clinical Research Centre, Medical University of Bialystok, 15-089, Bialystok, Poland.
  • Ciborowski M; Clinical Research Centre, Medical University of Bialystok, 15-089, Bialystok, Poland.
  • Szczerbinski L; Clinical Research Centre, Medical University of Bialystok, 15-089, Bialystok, Poland.
  • Kretowski A; Clinical Research Centre, Medical University of Bialystok, 15-089, Bialystok, Poland.
  • Desler C; Center for Healthy Aging, Department of Cellular and Molecular Medicine, University of Copenhagen, Blegdamsvej 3B, 2200, Copenhagen, Denmark.
  • Tiano L; Department of Life and Environmental Sciences (DISVA), Polytechnic University of Marche, via Brecce Bianche, Ancona, Italy.
  • Orlando P; Department of Life and Environmental Sciences (DISVA), Polytechnic University of Marche, via Brecce Bianche, Ancona, Italy.
  • Martinussen T; Department of Public Health, Faculty of Health and Medical Sciences, University of Copenhagen, Øster Farimagsgade 5, 1014, Copenhagen, Denmark.
  • Olsen LH; The LIFEPHARM Centre, Department of Veterinary and Animal Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Ridebanevej 9, 1870, Frederiksberg, Denmark.
  • Larsen S; Xlab, Center for Healthy Aging, Department of Biomedical Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, Blegdamsvej 3B, 2200, Copenhagen, Denmark. stelar@sund.ku.dk.
Sci Rep ; 11(1): 2167, 2021 01 26.
Article em En | MEDLINE | ID: mdl-33500513

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Mitocôndrias Hepáticas / Atorvastatina / Mitocôndrias Cardíacas / Mitocôndrias Musculares / Obesidade Limite: Animals Idioma: En Ano de publicação: 2021 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Mitocôndrias Hepáticas / Atorvastatina / Mitocôndrias Cardíacas / Mitocôndrias Musculares / Obesidade Limite: Animals Idioma: En Ano de publicação: 2021 Tipo de documento: Article