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Genetically defined favourable adiposity is not associated with a clinically meaningful difference in clinical course in people with type 2 diabetes but does associate with a favourable metabolic profile.
Heald, Adrian H; Martin, Susan; Fachim, Helene; Green, Harry D; Young, Katherine G; Malipatil, Nagaraj; Siddals, Kirk; Cortes, Gabriela; Tyrrell, Jessica; Wood, Andrew R; Beaumont, Robin N; Frayling, Timothy M; Donn, Rachelle; Narayanan, Ram Prakash; Ollier, William; Gibson, Martin; Yaghootkar, Hanieh.
Afiliação
  • Heald AH; The Faculty of Biology, Medicine and Health and Manchester Academic Health Sciences Centre, University of Manchester, Manchester, UK.
  • Martin S; Department of Diabetes and Endocrinology, Salford Royal Hospital, Salford, UK.
  • Fachim H; Genetics of Complex Traits, University of Exeter Medical School, University of Exeter, RILD Level 3, Royal Devon & Exeter Hospital, Exeter, UK.
  • Green HD; The Faculty of Biology, Medicine and Health and Manchester Academic Health Sciences Centre, University of Manchester, Manchester, UK.
  • Young KG; Department of Diabetes and Endocrinology, Salford Royal Hospital, Salford, UK.
  • Malipatil N; Genetics of Complex Traits, University of Exeter Medical School, University of Exeter, RILD Level 3, Royal Devon & Exeter Hospital, Exeter, UK.
  • Siddals K; Genetics of Complex Traits, University of Exeter Medical School, University of Exeter, RILD Level 3, Royal Devon & Exeter Hospital, Exeter, UK.
  • Cortes G; The Faculty of Biology, Medicine and Health and Manchester Academic Health Sciences Centre, University of Manchester, Manchester, UK.
  • Tyrrell J; Department of Diabetes and Endocrinology, Salford Royal Hospital, Salford, UK.
  • Wood AR; The Faculty of Biology, Medicine and Health and Manchester Academic Health Sciences Centre, University of Manchester, Manchester, UK.
  • Beaumont RN; Department of Diabetes and Endocrinology, Salford Royal Hospital, Salford, UK.
  • Frayling TM; General Directorate for Quality and Health Education, Mexico City, Mexico.
  • Donn R; Genetics of Complex Traits, University of Exeter Medical School, University of Exeter, RILD Level 3, Royal Devon & Exeter Hospital, Exeter, UK.
  • Narayanan RP; Genetics of Complex Traits, University of Exeter Medical School, University of Exeter, RILD Level 3, Royal Devon & Exeter Hospital, Exeter, UK.
  • Ollier W; Genetics of Complex Traits, University of Exeter Medical School, University of Exeter, RILD Level 3, Royal Devon & Exeter Hospital, Exeter, UK.
  • Gibson M; Genetics of Complex Traits, University of Exeter Medical School, University of Exeter, RILD Level 3, Royal Devon & Exeter Hospital, Exeter, UK.
  • Yaghootkar H; The Faculty of Biology, Medicine and Health and Manchester Academic Health Sciences Centre, University of Manchester, Manchester, UK.
Diabet Med ; 38(9): e14531, 2021 09.
Article em En | MEDLINE | ID: mdl-33501652
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Pressão Sanguínea / Predisposição Genética para Doença / Diabetes Mellitus Tipo 2 / Adiposidade / Metaboloma / Obesidade Tipo de estudo: Clinical_trials / Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2021 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Pressão Sanguínea / Predisposição Genética para Doença / Diabetes Mellitus Tipo 2 / Adiposidade / Metaboloma / Obesidade Tipo de estudo: Clinical_trials / Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Ano de publicação: 2021 Tipo de documento: Article