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Inhibition of MDM2 Promotes Antitumor Responses in p53 Wild-Type Cancer Cells through Their Interaction with the Immune and Stromal Microenvironment.
Wang, Hui Qin; Mulford, Iain J; Sharp, Fiona; Liang, Jinsheng; Kurtulus, Sema; Trabucco, Gina; Quinn, David S; Longmire, Tyler A; Patel, Nidhi; Patil, Roshani; Shirley, Matthew D; Chen, Yan; Wang, Hao; Ruddy, David A; Fabre, Claire; Williams, Juliet A; Hammerman, Peter S; Mataraza, Jennifer; Platzer, Barbara; Halilovic, Ensar.
Afiliação
  • Wang HQ; Novartis Institutes for BioMedical Research, Cambridge, Massachusetts.
  • Mulford IJ; Novartis Institutes for BioMedical Research, Cambridge, Massachusetts.
  • Sharp F; Novartis Institutes for BioMedical Research, Cambridge, Massachusetts.
  • Liang J; Novartis Institutes for BioMedical Research, Cambridge, Massachusetts.
  • Kurtulus S; Novartis Institutes for BioMedical Research, Cambridge, Massachusetts.
  • Trabucco G; Novartis Institutes for BioMedical Research, Cambridge, Massachusetts.
  • Quinn DS; Novartis Institutes for BioMedical Research, Cambridge, Massachusetts.
  • Longmire TA; Novartis Institutes for BioMedical Research, Cambridge, Massachusetts.
  • Patel N; Novartis Institutes for BioMedical Research, Cambridge, Massachusetts.
  • Patil R; Novartis Institutes for BioMedical Research, Cambridge, Massachusetts.
  • Shirley MD; Novartis Institutes for BioMedical Research, Cambridge, Massachusetts.
  • Chen Y; Novartis Institutes for BioMedical Research, Cambridge, Massachusetts.
  • Wang H; Novartis Institutes for BioMedical Research, Cambridge, Massachusetts.
  • Ruddy DA; Novartis Institutes for BioMedical Research, Cambridge, Massachusetts.
  • Fabre C; Novartis Institutes for BioMedical Research, Basel, Switzerland.
  • Williams JA; Novartis Institutes for BioMedical Research, Cambridge, Massachusetts.
  • Hammerman PS; Novartis Institutes for BioMedical Research, Cambridge, Massachusetts.
  • Mataraza J; Novartis Institutes for BioMedical Research, Cambridge, Massachusetts.
  • Platzer B; Novartis Institutes for BioMedical Research, Cambridge, Massachusetts.
  • Halilovic E; Novartis Institutes for BioMedical Research, Cambridge, Massachusetts. ensar.halilovic@novartis.com.
Cancer Res ; 81(11): 3079-3091, 2021 06 01.
Article em En | MEDLINE | ID: mdl-33504557
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Regulação Neoplásica da Expressão Gênica / Proteína Supressora de Tumor p53 / Células Estromais / Neoplasias do Colo / Linfócitos T CD8-Positivos / Proteínas Proto-Oncogênicas c-mdm2 / Microambiente Tumoral Tipo de estudo: Prognostic_studies Limite: Animals / Female / Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Regulação Neoplásica da Expressão Gênica / Proteína Supressora de Tumor p53 / Células Estromais / Neoplasias do Colo / Linfócitos T CD8-Positivos / Proteínas Proto-Oncogênicas c-mdm2 / Microambiente Tumoral Tipo de estudo: Prognostic_studies Limite: Animals / Female / Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article