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Urine Tenofovir Levels Measured Using a Novel Immunoassay Predict Human Immunodeficiency Virus Protection.
Stalter, Randy M; Baeten, Jared M; Donnell, Deborah; Spinelli, Matthew A; Glidden, David V; Rodrigues, Warren C; Wang, Guohong; Vincent, Michael; Mugo, Nelly; Mujugira, Andrew; Marzinke, Mark; Hendrix, Craig; Gandhi, Monica.
Afiliação
  • Stalter RM; Department of Global Health, University of Washington, Seattle, Washington, USA.
  • Baeten JM; Department of Epidemiology, University of Washington, Seattle, Washington, USA.
  • Donnell D; Department of Global Health, University of Washington, Seattle, Washington, USA.
  • Spinelli MA; Department of Epidemiology, University of Washington, Seattle, Washington, USA.
  • Glidden DV; Department of Medicine, University of Washington, Seattle, Washington, USA.
  • Rodrigues WC; Department of Global Health, University of Washington, Seattle, Washington, USA.
  • Wang G; Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, Seattle, Washington, USA.
  • Vincent M; Division of HIV, ID, and Global Medicine, University of California-San Francisco, San Francisco, California, USA.
  • Mugo N; Division of HIV, ID, and Global Medicine, University of California-San Francisco, San Francisco, California, USA.
  • Mujugira A; Toxicology Division, Abbott Rapid Diagnostics, Pomona, California, USA.
  • Marzinke M; Toxicology Division, Abbott Rapid Diagnostics, Pomona, California, USA.
  • Hendrix C; Toxicology Division, Abbott Rapid Diagnostics, Pomona, California, USA.
  • Gandhi M; Department of Global Health, University of Washington, Seattle, Washington, USA.
Clin Infect Dis ; 72(3): 486-489, 2021 02 01.
Article em En | MEDLINE | ID: mdl-33527128
ABSTRACT
New tools are needed to support pre-exposure prophylaxis (PrEP) adherence for human immunodeficiency virus (HIV) prevention, including those that enable real-time feedback. In a large, completed PrEP trial, adequate urine tenofovir levels measured using a novel immunoassay predicted HIV protection and showed good sensitivity and specificity for detectable plasma tenofovir.
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Infecções por HIV / Fármacos Anti-HIV / Profilaxia Pré-Exposição Tipo de estudo: Prognostic_studies / Risk_factors_studies Limite: Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Infecções por HIV / Fármacos Anti-HIV / Profilaxia Pré-Exposição Tipo de estudo: Prognostic_studies / Risk_factors_studies Limite: Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article