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Improved in vivo PET imaging of the adenosine A2A receptor in the brain using [18F]FLUDA, a deuterated radiotracer with high metabolic stability.
Lai, Thu Hang; Toussaint, Magali; Teodoro, Rodrigo; Dukic-Stefanovic, Sladjana; Gündel, Daniel; Ludwig, Friedrich-Alexander; Wenzel, Barbara; Schröder, Susann; Sattler, Bernhard; Moldovan, Rares-Petru; Falkenburger, Björn H; Sabri, Osama; Deuther-Conrad, Winnie; Brust, Peter.
Afiliação
  • Lai TH; Department of Neuroradiopharmaceuticals, Institute of Radiopharmaceutical Cancer Research, Helmholtz-Zentrum Dresden-Rossendorf, Leipzig, Germany. t.lai@hzdr.de.
  • Toussaint M; Department of Research and Development, ROTOP Pharmaka Ltd., Dresden, Germany. t.lai@hzdr.de.
  • Teodoro R; Department of Neuroradiopharmaceuticals, Institute of Radiopharmaceutical Cancer Research, Helmholtz-Zentrum Dresden-Rossendorf, Leipzig, Germany. m.toussaint@hzdr.de.
  • Dukic-Stefanovic S; Department of Neuroradiopharmaceuticals, Institute of Radiopharmaceutical Cancer Research, Helmholtz-Zentrum Dresden-Rossendorf, Leipzig, Germany.
  • Gündel D; Department of Neuroradiopharmaceuticals, Institute of Radiopharmaceutical Cancer Research, Helmholtz-Zentrum Dresden-Rossendorf, Leipzig, Germany.
  • Ludwig FA; Department of Neuroradiopharmaceuticals, Institute of Radiopharmaceutical Cancer Research, Helmholtz-Zentrum Dresden-Rossendorf, Leipzig, Germany.
  • Wenzel B; Department of Neuroradiopharmaceuticals, Institute of Radiopharmaceutical Cancer Research, Helmholtz-Zentrum Dresden-Rossendorf, Leipzig, Germany.
  • Schröder S; Department of Neuroradiopharmaceuticals, Institute of Radiopharmaceutical Cancer Research, Helmholtz-Zentrum Dresden-Rossendorf, Leipzig, Germany.
  • Sattler B; Department of Research and Development, ROTOP Pharmaka Ltd., Dresden, Germany.
  • Moldovan RP; Department of Nuclear Medicine, University Hospital Leipzig, Leipzig, Germany.
  • Falkenburger BH; Department of Neuroradiopharmaceuticals, Institute of Radiopharmaceutical Cancer Research, Helmholtz-Zentrum Dresden-Rossendorf, Leipzig, Germany.
  • Sabri O; Department of Neurology, Dresden University Medical Center, Dresden, Germany.
  • Deuther-Conrad W; Department of Nuclear Medicine, University Hospital Leipzig, Leipzig, Germany.
  • Brust P; Department of Neuroradiopharmaceuticals, Institute of Radiopharmaceutical Cancer Research, Helmholtz-Zentrum Dresden-Rossendorf, Leipzig, Germany.
Eur J Nucl Med Mol Imaging ; 48(9): 2727-2736, 2021 08.
Article em En | MEDLINE | ID: mdl-33532910
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Receptor A2A de Adenosina / Tomografia por Emissão de Pósitrons Limite: Animals Idioma: En Ano de publicação: 2021 Tipo de documento: Article
Texto completo
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PubMed Links
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Receptor A2A de Adenosina / Tomografia por Emissão de Pósitrons Limite: Animals Idioma: En Ano de publicação: 2021 Tipo de documento: Article