[Disseminated aspergillosis due to Aspergillus udagawae during immunosuppressive treatment for myelodysplastic syndrome].
Rinsho Ketsueki
; 62(1): 51-54, 2021.
Article
em Ja
| MEDLINE
| ID: mdl-33551426
ABSTRACT
An 80 year old male who had received immunosuppressive therapy for myelodysplastic syndrome presented with fever, fatigue, and elevated serum Aspergillus antigen. Computed tomography revealed infiltrative shadows in the left lower lung and subcutaneous nodules. A polymerase chain reaction assay from lung and subcutaneous nodule samples identified the presence Aspergillus udagawae. A. udagawae is a cryptic species that shares similar morphological characteristics with A. fumigatus but genetically differs from the latter in its susceptibility to antifungal drugs. When immunosuppressed patients with hematological malignancies develop disseminated aspergillosis, biopsy and fungal tests are crucial to identify the causative fungus, including cryptic species, for deciding the appropriate therapeutic intervention.
Palavras-chave
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Aspergilose
/
Síndromes Mielodisplásicas
Tipo de estudo:
Diagnostic_studies
/
Prognostic_studies
Limite:
Aged80
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Humans
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Male
Idioma:
Ja
Ano de publicação:
2021
Tipo de documento:
Article