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The thymoproteasome hardwires the TCR repertoire of CD8+ T cells in the cortex independent of negative selection.
Ohigashi, Izumi; Frantzeskakis, Melina; Jacques, Alison; Fujimori, Sayumi; Ushio, Aya; Yamashita, Fusano; Ishimaru, Naozumi; Yin, Da; Cam, Margaret; Kelly, Michael C; Awasthi, Parirokh; Takada, Kensuke; Takahama, Yousuke.
Afiliação
  • Ohigashi I; Division of Experimental Immunology, Institute of Advanced Medical Sciences, University of Tokushima, Tokushima, Japan.
  • Frantzeskakis M; Experimental Immunology Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD.
  • Jacques A; Experimental Immunology Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD.
  • Fujimori S; Division of Experimental Immunology, Institute of Advanced Medical Sciences, University of Tokushima, Tokushima, Japan.
  • Ushio A; Experimental Immunology Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD.
  • Yamashita F; Division of Experimental Immunology, Institute of Advanced Medical Sciences, University of Tokushima, Tokushima, Japan.
  • Ishimaru N; Department of Oral Molecular Pathology, Tokushima University Graduate School of Biomedical Sciences, Tokushima, Japan.
  • Yin D; Collaborative Bioinformatics Resource, National Cancer Institute, National Institutes of Health, Bethesda, MD.
  • Cam M; Collaborative Bioinformatics Resource, National Cancer Institute, National Institutes of Health, Bethesda, MD.
  • Kelly MC; Single Cell Analysis Facility, National Cancer Institute, National Institutes of Health, Bethesda, MD.
  • Awasthi P; Transgenic Mouse Model Laboratory, Frederick National Laboratory for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD.
  • Takada K; Laboratory of Molecular Medicine, Faculty of Veterinary Medicine, Hokkaido University, Sapporo, Japan.
  • Takahama Y; Experimental Immunology Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD.
J Exp Med ; 218(4)2021 04 05.
Article em En | MEDLINE | ID: mdl-33555295
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Timo / Receptores de Antígenos de Linfócitos T alfa-beta / Linfócitos T CD8-Positivos / Complexo de Endopeptidases do Proteassoma / Células Epiteliais Limite: Animals Idioma: En Ano de publicação: 2021 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Timo / Receptores de Antígenos de Linfócitos T alfa-beta / Linfócitos T CD8-Positivos / Complexo de Endopeptidases do Proteassoma / Células Epiteliais Limite: Animals Idioma: En Ano de publicação: 2021 Tipo de documento: Article