Relevance of Liquid-Liquid Phase Separation of Supersaturated Solution in Oral Absorption of Albendazole from Amorphous Solid Dispersions.

Suzuki, Kyosuke; Kawakami, Kohsaku; Fukiage, Masafumi; Oikawa, Michinori; Nishida, Yohei; Matsuda, Maki; Fujita, Takuya.

Afiliação

Suzuki K; Pharmaceutical and ADMET Research Department, Daiichi Sankyo RD Novare Co., Ltd., 1-16-13, Kitakasai, Edogawa-ku, Tokyo 134-8630, Japan.
Kawakami K; Research Center for Functionals Materials, National Institute for Materials Science, 1-1 Namiki, Tsukuba, Ibaraki 305-0044, Japan.
Fukiage M; Pharmaceutical R&D, Ono Pharmaceutical Co., Ltd., 3-3-1, Sakurai, Shimamoto-cho, Mishima-gun, Osaka 618-8585, Japan.
Oikawa M; Pharmaceutical Development Department, Sawai Pharmaceutical Co., Ltd., 5-2-30, Miyahara, Yodogawa-ku, Osaka 532-0003, Japan.
Nishida Y; Technology Research & Development, Sumitomo Dainippon Pharma Co., Ltd., 33-94, Enoki-cho, Suita, Osaka 564-0053, Japan.
Matsuda M; Research & Development Division, Towa Pharmaceutical Co., Ltd., 134, Chudoji Minami-machi, Shimogyo-ku, Kyoto 600-8813, Japan.
Fujita T; College of Pharmaceutical Sciences, Ritsumeikan University, 1-1-1 Noji-Higashi, Kusatsu, Shiga 525-8577, Japan.

Pharmaceutics ; 13(2)2021 Feb 05.

Article em En | MEDLINE | ID: mdl-33562770