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Collaboration between the Fab and Fc contribute to maximal protection against SARS-CoV-2 in nonhuman primates following NVX-CoV2373 subunit vaccine with Matrix-M™ vaccination.
Gorman, Matthew J; Patel, Nita; Guebre-Xabier, Mimi; Zhu, Alex; Atyeo, Caroline; Pullen, Krista M; Loos, Carolin; Goez-Gazi, Yenny; Carrion, Ricardo; Tian, Jing-Hui; Yaun, Dansu; Bowman, Kathryn; Zhou, Bin; Maciejewski, Sonia; McGrath, Marisa E; Logue, James; Frieman, Matthew B; Montefiori, David; Mann, Colin; Schendel, Sharon; Amanat, Fatima; Krammer, Florian; Saphire, Erica Ollmann; Lauffenburger, Douglas; Greene, Ann M; Portnoff, Alyse D; Massare, Michael J; Ellingsworth, Larry; Glenn, Gregory; Smith, Gale; Alter, Galit.
Afiliação
  • Gorman MJ; Ragon Institute of MGH, MIT, and Harvard, Cambridge, MA 02139, USA.
  • Patel N; Novavax, Inc., 21 Firstfield Road, Gaithersburg, MD 20878, USA.
  • Guebre-Xabier M; Novavax, Inc., 21 Firstfield Road, Gaithersburg, MD 20878, USA.
  • Zhu A; Ragon Institute of MGH, MIT, and Harvard, Cambridge, MA 02139, USA.
  • Atyeo C; Ragon Institute of MGH, MIT, and Harvard, Cambridge, MA 02139, USA.
  • Pullen KM; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
  • Loos C; Ragon Institute of MGH, MIT, and Harvard, Cambridge, MA 02139, USA.
  • Goez-Gazi Y; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
  • Carrion R; Texas Biomedical Research Institute. 8715 West Military Drive, San Antonio, TX 78227, USA.
  • Tian JH; Texas Biomedical Research Institute. 8715 West Military Drive, San Antonio, TX 78227, USA.
  • Yaun D; Novavax, Inc., 21 Firstfield Road, Gaithersburg, MD 20878, USA.
  • Bowman K; Ragon Institute of MGH, MIT, and Harvard, Cambridge, MA 02139, USA.
  • Zhou B; Ragon Institute of MGH, MIT, and Harvard, Cambridge, MA 02139, USA.
  • Maciejewski S; Novavax, Inc., 21 Firstfield Road, Gaithersburg, MD 20878, USA.
  • McGrath ME; Novavax, Inc., 21 Firstfield Road, Gaithersburg, MD 20878, USA.
  • Logue J; University of Maryland, School of Medicine, 685 West Baltimore St, Baltimore, MD 21201, USA.
  • Frieman MB; University of Maryland, School of Medicine, 685 West Baltimore St, Baltimore, MD 21201, USA.
  • Montefiori D; University of Maryland, School of Medicine, 685 West Baltimore St, Baltimore, MD 21201, USA.
  • Mann C; Department of Surgery, Duke University Medical Center, Durham, NC 27710, USA.
  • Schendel S; La Jolla Institute for Immunology, La Jolla, CA 92037, USA.
  • Amanat F; La Jolla Institute for Immunology, La Jolla, CA 92037, USA.
  • Krammer F; Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
  • Saphire EO; Department of Microbiology, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
  • Lauffenburger D; La Jolla Institute for Immunology, La Jolla, CA 92037, USA.
  • Greene AM; Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
  • Portnoff AD; Novavax, Inc., 21 Firstfield Road, Gaithersburg, MD 20878, USA.
  • Massare MJ; Novavax, Inc., 21 Firstfield Road, Gaithersburg, MD 20878, USA.
  • Ellingsworth L; Novavax, Inc., 21 Firstfield Road, Gaithersburg, MD 20878, USA.
  • Glenn G; Novavax, Inc., 21 Firstfield Road, Gaithersburg, MD 20878, USA.
  • Smith G; Novavax, Inc., 21 Firstfield Road, Gaithersburg, MD 20878, USA.
  • Alter G; Novavax, Inc., 21 Firstfield Road, Gaithersburg, MD 20878, USA.
bioRxiv ; 2021 Feb 05.
Article em En | MEDLINE | ID: mdl-33564763
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Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2021 Tipo de documento: Article
Texto completo
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PubMed Links
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Texto completo: 1 Base de dados: MEDLINE Idioma: En Ano de publicação: 2021 Tipo de documento: Article