PspC domain-containing protein (PCP) determines Streptococcus mutans biofilm formation through bacterial extracellular DNA release and platelet adhesion in experimental endocarditis.

Jung, Chiau-Jing; Hsu, Chih-Chieh; Chen, Jeng-Wei; Cheng, Hung-Wei; Yuan, Chang-Tsu; Kuo, Yu-Min; Hsu, Ron-Bin; Chia, Jean-San

Jung, Chiau-Jing; Hsu, Chih-Chieh; Chen, Jeng-Wei; Cheng, Hung-Wei; Yuan, Chang-Tsu; Kuo, Yu-Min; Hsu, Ron-Bin; Chia, Jean-San.

Afiliação

Jung CJ; Department of Microbiology and Immunology, School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan.
Hsu CC; Graduate Institute of Oral Biology, School of Dentistry, National Taiwan University, Taipei, Taiwan.
Chen JW; Division of Cardiovascular Surgery, Department of Surgery, National Taiwan University Hospital, Taipei, Taiwan.
Cheng HW; Graduate Institute of Clinical Medicine, College of Medicine, National Taiwan University, Taipei, Taiwan.
Yuan CT; Graduate Institute of Microbiology, College of Medicine, National Taiwan University, Taipei, Taiwan.
Kuo YM; Graduate Institute of Clinical Medicine, College of Medicine, National Taiwan University, Taipei, Taiwan.
Hsu RB; Department of Pathology, National Taiwan University Cancer Center, Taipei, Taiwan.
Chia JS; Department of Pathology, National Taiwan University Hospital, Taipei, Taiwan.

PLoS Pathog ; 17(2): e1009289, 2021 02.

Article em En | MEDLINE | ID: mdl-33577624

Assuntos

Proteínas de Bactérias/metabolismo; Biofilmes/crescimento & desenvolvimento; DNA Bacteriano/metabolismo; Endocardite/microbiologia; Adesividade Plaquetária; Infecções Estreptocócicas/microbiologia; Streptococcus mutans/crescimento & desenvolvimento; Animais; Proteínas de Bactérias/genética; Endocardite/metabolismo; Endocardite/patologia; Espaço Extracelular/metabolismo; Voluntários Saudáveis; Interações Hospedeiro-Patógeno; Humanos; Ratos; Infecções Estreptocócicas/metabolismo; Infecções Estreptocócicas/patologia; Streptococcus mutans/genética

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Infecções Estreptocócicas / Streptococcus mutans / Proteínas de Bactérias / DNA Bacteriano / Adesividade Plaquetária / Biofilmes / Endocardite Limite: Animals / Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article

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