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Granulovirus PK-1 kinase activity relies on a side-to-side dimerization mode centered on the regulatory αC helix.
Oliver, Michael R; Horne, Christopher R; Shrestha, Safal; Keown, Jeremy R; Liang, Lung-Yu; Young, Samuel N; Sandow, Jarrod J; Webb, Andrew I; Goldstone, David C; Lucet, Isabelle S; Kannan, Natarajan; Metcalf, Peter; Murphy, James M.
Afiliação
  • Oliver MR; School of Biological Sciences, University of Auckland, Auckland, New Zealand.
  • Horne CR; School of Biological Sciences, University of Edinburgh, Edinburgh, UK.
  • Shrestha S; Walter and Eliza Hall Institute of Medical Research, Parkville, VIC, Australia.
  • Keown JR; Department of Medical Biology, University of Melbourne, Parkville, VIC, Australia.
  • Liang LY; Institute of Bioinformatics, University of Georgia, Athens, GA, USA.
  • Young SN; School of Biological Sciences, University of Auckland, Auckland, New Zealand.
  • Sandow JJ; Division of Structural Biology, Wellcome Centre for Human Genetics, University of Oxford, Oxford, UK.
  • Webb AI; Walter and Eliza Hall Institute of Medical Research, Parkville, VIC, Australia.
  • Goldstone DC; Department of Medical Biology, University of Melbourne, Parkville, VIC, Australia.
  • Lucet IS; Walter and Eliza Hall Institute of Medical Research, Parkville, VIC, Australia.
  • Kannan N; Walter and Eliza Hall Institute of Medical Research, Parkville, VIC, Australia.
  • Metcalf P; Department of Medical Biology, University of Melbourne, Parkville, VIC, Australia.
  • Murphy JM; Walter and Eliza Hall Institute of Medical Research, Parkville, VIC, Australia.
Nat Commun ; 12(1): 1002, 2021 02 12.
Article em En | MEDLINE | ID: mdl-33579933
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Proteínas Quinases / Dimerização / Granulovirus Idioma: En Ano de publicação: 2021 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Proteínas Quinases / Dimerização / Granulovirus Idioma: En Ano de publicação: 2021 Tipo de documento: Article