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Targeting galectin-3 with a high-affinity antibody for inhibition of high-grade serous ovarian cancer and other MUC16/CA-125-expressing malignancies.
Stasenko, Marina; Smith, Evan; Yeku, Oladapo; Park, Kay J; Laster, Ian; Lee, Kwangkook; Walderich, Sven; Spriggs, Elizabeth; Rueda, Bo; Weigelt, Britta; Zamarin, Dmitriy; Rao, Thapi Dharma; Spriggs, David R.
Afiliação
  • Stasenko M; Gynecology Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, 10065, USA.
  • Smith E; Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, NYU Langone Health, New York, NY, 10016, USA.
  • Yeku O; Gynecology Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, 10065, USA.
  • Park KJ; Division of Hematology-Oncology, Massachusetts General Hospital, 55 Fruit St, Boston, MA, 02114, USA.
  • Laster I; Department of Medicine, Massachusetts General Hospital, Boston, MA, 02114, USA.
  • Lee K; Gynecology Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, 10065, USA.
  • Walderich S; Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY, 10065, USA.
  • Spriggs E; Division of Hematology-Oncology, Massachusetts General Hospital, 55 Fruit St, Boston, MA, 02114, USA.
  • Rueda B; Division of Hematology-Oncology, Massachusetts General Hospital, 55 Fruit St, Boston, MA, 02114, USA.
  • Weigelt B; Department of Medicine, Massachusetts General Hospital, Boston, MA, 02114, USA.
  • Zamarin D; Department of Medicine, University of California San Francisco Medical Center, San Francisco, CA, 94143, USA.
  • Rao TD; Arnold Arboretum of Harvard University, Boston, MA, 02131, USA.
  • Spriggs DR; Department of Obstetrics and Gynecology, Vincent Center for Reproductive Biology, Massachusetts General Hospital, Boston, MA, 02114, USA.
Sci Rep ; 11(1): 3718, 2021 02 12.
Article em En | MEDLINE | ID: mdl-33580170

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias Ovarianas / Proteínas Sanguíneas / Antígeno Ca-125 / Galectinas / Proteínas de Membrana / Anticorpos Monoclonais Limite: Animals Idioma: En Ano de publicação: 2021 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Neoplasias Ovarianas / Proteínas Sanguíneas / Antígeno Ca-125 / Galectinas / Proteínas de Membrana / Anticorpos Monoclonais Limite: Animals Idioma: En Ano de publicação: 2021 Tipo de documento: Article