A case of immune checkpoint inhibitor-associated gastroenteritis detected by ultrasonography.
J Clin Ultrasound
; 49(6): 605-609, 2021 Jul.
Article
em En
| MEDLINE
| ID: mdl-33580597
ABSTRACT
While immune checkpoint inhibitors (ICIs) have antitumor effects, they also have characteristic side effects, including colitis. However, gastritis has rarely been reported. We report a case of a patient with lung adenocarcinoma who presented with epigastric pain and diarrhea following pembrolizumab administration. Sonography of the abdomen demonstrated diffuse, although mild, gastric wall thickening (mainly in the submucosa), as well as a slight decrease in echogenicity throughout the gastric wall. While the mucosal surface was relatively smooth, color Doppler examination showed increased vascularity. Esophagogastroduodenoscopy and pathological examination confirmed the diagnosis of ICI-related gastroenteritis.
Palavras-chave
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Gastroenterite
/
Inibidores de Checkpoint Imunológico
Tipo de estudo:
Diagnostic_studies
/
Risk_factors_studies
Limite:
Humans
Idioma:
En
Ano de publicação:
2021
Tipo de documento:
Article