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A common SNP risk variant MT1-MMP causative for Dupuytren's disease has a specific defect in collagenolytic activity.
Itoh, Yoshifumi; Ng, Michael; Wiberg, Akira; Inoue, Katsuaki; Hirata, Narumi; Paiva, Katiucia Batista Silva; Ito, Noriko; Dzobo, Kim; Sato, Nanami; Gifford, Valentina; Fujita, Yasuyuki; Inada, Masaki; Furniss, Dominic.
Afiliação
  • Itoh Y; Kennedy Institute of Rheumatology, NDORMS, University of Oxford, Oxford OX3 7FY, UK. Electronic address: yoshi.itoh@kennedy.ox.ac.uk.
  • Ng M; Botnar Research Centre, NDORMS, University of Oxford, Oxford OX3 7HE, UK.
  • Wiberg A; Botnar Research Centre, NDORMS, University of Oxford, Oxford OX3 7HE, UK.
  • Inoue K; Diamond Light Source, Harwell Science & Innovation Campus, Didcot, Oxford, UK.
  • Hirata N; Kennedy Institute of Rheumatology, NDORMS, University of Oxford, Oxford OX3 7FY, UK; Department of Biotechnology and Life Science, Tokyo University of Agriculture and Technology, Tokyo, Japan.
  • Paiva KBS; Kennedy Institute of Rheumatology, NDORMS, University of Oxford, Oxford OX3 7FY, UK; Department of Anatomy, Institute of Biomedical Sciences, University of São Paulo, Brazil.
  • Ito N; Kennedy Institute of Rheumatology, NDORMS, University of Oxford, Oxford OX3 7FY, UK.
  • Dzobo K; Kennedy Institute of Rheumatology, NDORMS, University of Oxford, Oxford OX3 7FY, UK.
  • Sato N; Kennedy Institute of Rheumatology, NDORMS, University of Oxford, Oxford OX3 7FY, UK; Institute for Genetic Medicine, Division of Molecular Oncology, Hokkaido University, Sapporo, Hokkaido, Japan.
  • Gifford V; Kennedy Institute of Rheumatology, NDORMS, University of Oxford, Oxford OX3 7FY, UK.
  • Fujita Y; Institute for Genetic Medicine, Division of Molecular Oncology, Hokkaido University, Sapporo, Hokkaido, Japan; Department of Molecular Oncology, Kyoto University Medical School, Kyoto, Japan.
  • Inada M; Department of Biotechnology and Life Science, Tokyo University of Agriculture and Technology, Tokyo, Japan.
  • Furniss D; Botnar Research Centre, NDORMS, University of Oxford, Oxford OX3 7HE, UK. Electronic address: dominic.furniss@ndorms.ox.ac.uk.
Matrix Biol ; 97: 20-39, 2021 03.
Article em En | MEDLINE | ID: mdl-33592276
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Colágeno / Polimorfismo de Nucleotídeo Único / Contratura de Dupuytren / Metaloproteinase 14 da Matriz Tipo de estudo: Etiology_studies / Risk_factors_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Colágeno / Polimorfismo de Nucleotídeo Único / Contratura de Dupuytren / Metaloproteinase 14 da Matriz Tipo de estudo: Etiology_studies / Risk_factors_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article