Osteoclast-Like Giant Cells: Focus on Entities Relevant to Dermatopathology and Underlying Pathogenesis.
Am J Dermatopathol
; 43(3): 163-173, 2021 Mar 01.
Article
em En
| MEDLINE
| ID: mdl-33595228
ABSTRACT
ABSTRACT Osteoclast-like giant cells (OLGCs) resemble osteoclasts with their abundant cytoplasm and well-developed organelles. OLGCs are characteristic features of giant cell tumor of the tendon sheath and giant cell tumor of soft tissue but they have also been described in numerous other cutaneous conditions. The diagnostic and prognostic significance of the presence of OLGCs is unknown. Here, we summarize the clinical entities that can exhibit these cells to avoid a histological overlap, affecting diagnosis and management.
Texto completo:
1
Base de dados:
MEDLINE
Assunto principal:
Osteoclastos
/
Pele
/
Dermatopatias
/
Células Gigantes
Tipo de estudo:
Etiology_studies
/
Prognostic_studies
Limite:
Humans
Idioma:
En
Ano de publicação:
2021
Tipo de documento:
Article