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Synthesis, Structure-Activity Relationships, and Antiviral Activity of Allosteric Inhibitors of Flavivirus NS2B-NS3 Protease.
Nie, Shenyou; Yao, Yuan; Wu, Fangrui; Wu, Xiaowei; Zhao, Jidong; Hua, Yuanda; Wu, Jingyu; Huo, Tong; Lin, Yi-Lun; Kneubehl, Alexander R; Vogt, Megan B; Ferreon, Josephine; Rico-Hesse, Rebecca; Song, Yongcheng.
Afiliação
  • Nie S; Department of Pharmacology and Chemical Biology, Baylor College of Medicine, 1 Baylor Plaza, Houston, Texas 77030, United States.
  • Yao Y; Department of Pharmacology and Chemical Biology, Baylor College of Medicine, 1 Baylor Plaza, Houston, Texas 77030, United States.
  • Wu F; Department of Pharmacology and Chemical Biology, Baylor College of Medicine, 1 Baylor Plaza, Houston, Texas 77030, United States.
  • Wu X; Department of Pharmacology and Chemical Biology, Baylor College of Medicine, 1 Baylor Plaza, Houston, Texas 77030, United States.
  • Zhao J; Department of Pharmacology and Chemical Biology, Baylor College of Medicine, 1 Baylor Plaza, Houston, Texas 77030, United States.
  • Hua Y; Department of Pharmacology and Chemical Biology, Baylor College of Medicine, 1 Baylor Plaza, Houston, Texas 77030, United States.
  • Wu J; Department of Pharmacology and Chemical Biology, Baylor College of Medicine, 1 Baylor Plaza, Houston, Texas 77030, United States.
  • Huo T; Department of Pharmacology and Chemical Biology, Baylor College of Medicine, 1 Baylor Plaza, Houston, Texas 77030, United States.
  • Lin YL; Department of Pharmacology and Chemical Biology, Baylor College of Medicine, 1 Baylor Plaza, Houston, Texas 77030, United States.
  • Kneubehl AR; Department of Molecular Virology and Microbiology, Baylor College of Medicine, 1 Baylor Plaza, Houston, Texas 77030, United States.
  • Vogt MB; Department of Molecular Virology and Microbiology, Baylor College of Medicine, 1 Baylor Plaza, Houston, Texas 77030, United States.
  • Ferreon J; Intragrative Molecular and Biomedical Sciences Graduate Program, Baylor College of Medicine, 1 Baylor Plaza, Houston, Texas 77030, United States.
  • Rico-Hesse R; Department of Pharmacology and Chemical Biology, Baylor College of Medicine, 1 Baylor Plaza, Houston, Texas 77030, United States.
  • Song Y; Department of Molecular Virology and Microbiology, Baylor College of Medicine, 1 Baylor Plaza, Houston, Texas 77030, United States.
J Med Chem ; 64(5): 2777-2800, 2021 03 11.
Article em En | MEDLINE | ID: mdl-33596380
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Antivirais / Pirazinas / Proteínas Virais / Serina Endopeptidases / Inibidores de Serina Proteinase / Infecção por Zika virus Limite: Animals / Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Antivirais / Pirazinas / Proteínas Virais / Serina Endopeptidases / Inibidores de Serina Proteinase / Infecção por Zika virus Limite: Animals / Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article