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CERTL reduces C16 ceramide, amyloid-ß levels, and inflammation in a model of Alzheimer's disease.
Crivelli, Simone M; Luo, Qian; Stevens, Jo A A; Giovagnoni, Caterina; van Kruining, Daan; Bode, Gerard; den Hoedt, Sandra; Hobo, Barbara; Scheithauer, Anna-Lena; Walter, Jochen; Mulder, Monique T; Exley, Christopher; Mold, Matthew; Mielke, Michelle M; De Vries, Helga E; Wouters, Kristiaan; van den Hove, Daniel L A; Berkes, Dusan; Ledesma, María Dolores; Verhaagen, Joost; Losen, Mario; Bieberich, Erhard; Martinez-Martinez, Pilar.
Afiliação
  • Crivelli SM; Department of Psychiatry and Neuropsychology, School for Mental Health and Neuroscience, Maastricht University, Universiteitssingel 50, 6229 ER, Maastricht, the Netherlands.
  • Luo Q; Department of Physiology, University of Kentucky College of Medicine, Lexington, KY, USA.
  • Stevens JAA; Veterans Affairs Medical Center, Lexington, KY, 40502, USA.
  • Giovagnoni C; Department of Psychiatry and Neuropsychology, School for Mental Health and Neuroscience, Maastricht University, Universiteitssingel 50, 6229 ER, Maastricht, the Netherlands.
  • van Kruining D; Department of Psychiatry and Neuropsychology, School for Mental Health and Neuroscience, Maastricht University, Universiteitssingel 50, 6229 ER, Maastricht, the Netherlands.
  • Bode G; Department of Psychiatry and Neuropsychology, School for Mental Health and Neuroscience, Maastricht University, Universiteitssingel 50, 6229 ER, Maastricht, the Netherlands.
  • den Hoedt S; Department of Psychiatry and Neuropsychology, School for Mental Health and Neuroscience, Maastricht University, Universiteitssingel 50, 6229 ER, Maastricht, the Netherlands.
  • Hobo B; Department of Psychiatry and Neuropsychology, School for Mental Health and Neuroscience, Maastricht University, Universiteitssingel 50, 6229 ER, Maastricht, the Netherlands.
  • Scheithauer AL; Department of Internal Medicine, Laboratory Vascular Medicine, Erasmus MC University Medical Center, Rotterdam, the Netherlands.
  • Walter J; Laboratory for Neuroregeneration, Netherlands institute for Neuroscience, Amsterdam, the Netherlands.
  • Mulder MT; Department of Neurology, University Hospital Bonn, University of Bonn, Bonn, Germany.
  • Exley C; Department of Neurology, University Hospital Bonn, University of Bonn, Bonn, Germany.
  • Mold M; Department of Internal Medicine, Laboratory Vascular Medicine, Erasmus MC University Medical Center, Rotterdam, the Netherlands.
  • Mielke MM; The Birchall Centre, Lennard-Jones Laboratories, Keele University, Staffordshire, UK.
  • De Vries HE; The Birchall Centre, Lennard-Jones Laboratories, Keele University, Staffordshire, UK.
  • Wouters K; Division of Epidemiology, Department of Health Science Research, and Department of Neurology, Mayo Clinic Rochester, Rochester, MN, USA.
  • van den Hove DLA; Department of Molecular Cell Biology and Immunology, Amsterdam Neuroscience, Amsterdam UMC, Amsterdam, the Netherlands.
  • Berkes D; Department of Internal Medicine, Maastricht University Medical Centre, Maastricht, the Netherlands.
  • Ledesma MD; Cardiovascular Research Institute Maastricht (CARIM), Maastricht, the Netherlands.
  • Verhaagen J; Department of Psychiatry, Psychosomatics and Psychotherapy, University of Wuerzburg, Wuerzburg, Germany.
  • Losen M; Department of Organic Chemistry, Slovak University of Technology, Radlinského 9, 81237, Bratislava, Slovak Republic.
  • Bieberich E; Department of Molecular Neuropathology, Centro de Biología Molecular "Severo Ochoa" (CSIC-UAM), Madrid, Spain.
  • Martinez-Martinez P; Laboratory for Neuroregeneration, Netherlands institute for Neuroscience, Amsterdam, the Netherlands.
Alzheimers Res Ther ; 13(1): 45, 2021 02 17.
Article em En | MEDLINE | ID: mdl-33597019
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Doença de Alzheimer Limite: Animals Idioma: En Ano de publicação: 2021 Tipo de documento: Article
Texto completo
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PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Doença de Alzheimer Limite: Animals Idioma: En Ano de publicação: 2021 Tipo de documento: Article