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Oxidized phosphatidylcholines found in multiple sclerosis lesions mediate neurodegeneration and are neutralized by microglia.
Dong, Yifei; D'Mello, Charlotte; Pinsky, William; Lozinski, Brian M; Kaushik, Deepak K; Ghorbani, Samira; Moezzi, Dorsa; Brown, Dennis; Melo, Francisca C; Zandee, Stephanie; Vo, Tina; Prat, Alexandre; Whitehead, Shawn N; Yong, V Wee.
Afiliação
  • Dong Y; Hotchkiss Brain Institute and the Department of Clinical Neuroscience, University of Calgary, Calgary, Alberta, Canada.
  • D'Mello C; Hotchkiss Brain Institute and the Department of Clinical Neuroscience, University of Calgary, Calgary, Alberta, Canada.
  • Pinsky W; Department of Anatomy and Cell Biology, Western University, London, Ontario, Canada.
  • Lozinski BM; Hotchkiss Brain Institute and the Department of Clinical Neuroscience, University of Calgary, Calgary, Alberta, Canada.
  • Kaushik DK; Hotchkiss Brain Institute and the Department of Clinical Neuroscience, University of Calgary, Calgary, Alberta, Canada.
  • Ghorbani S; Hotchkiss Brain Institute and the Department of Clinical Neuroscience, University of Calgary, Calgary, Alberta, Canada.
  • Moezzi D; Hotchkiss Brain Institute and the Department of Clinical Neuroscience, University of Calgary, Calgary, Alberta, Canada.
  • Brown D; Hotchkiss Brain Institute and the Department of Clinical Neuroscience, University of Calgary, Calgary, Alberta, Canada.
  • Melo FC; Hotchkiss Brain Institute and the Department of Clinical Neuroscience, University of Calgary, Calgary, Alberta, Canada.
  • Zandee S; Neuroimmunology Unit, The Research Center of the Centre Hospitalier de l'Université de Montréal (CRCHUM), Department of Neuroscience, Faculty of Medicine, Université de Montréal, Montréal, Québec, Canada.
  • Vo T; Hotchkiss Brain Institute and the Department of Clinical Neuroscience, University of Calgary, Calgary, Alberta, Canada.
  • Prat A; Neuroimmunology Unit, The Research Center of the Centre Hospitalier de l'Université de Montréal (CRCHUM), Department of Neuroscience, Faculty of Medicine, Université de Montréal, Montréal, Québec, Canada.
  • Whitehead SN; Department of Anatomy and Cell Biology, Western University, London, Ontario, Canada.
  • Yong VW; Hotchkiss Brain Institute and the Department of Clinical Neuroscience, University of Calgary, Calgary, Alberta, Canada. vyong@ucalgary.ca.
Nat Neurosci ; 24(4): 489-503, 2021 04.
Article em En | MEDLINE | ID: mdl-33603230
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Fosfatidilcolinas / Glicoproteínas de Membrana / Receptores Imunológicos / Microglia / Esclerose Múltipla / Degeneração Neural Limite: Animals / Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Fosfatidilcolinas / Glicoproteínas de Membrana / Receptores Imunológicos / Microglia / Esclerose Múltipla / Degeneração Neural Limite: Animals / Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article