A guide to creating design matrices for gene expression experiments.

Law, Charity W; Zeglinski, Kathleen; Dong, Xueyi; Alhamdoosh, Monther; Smyth, Gordon K; Ritchie, Matthew E

Law, Charity W; Zeglinski, Kathleen; Dong, Xueyi; Alhamdoosh, Monther; Smyth, Gordon K; Ritchie, Matthew E.

Afiliação

Law CW; The Walter and Eliza Hall Institute of Medical Research, Parkville, 3052, Australia.
Zeglinski K; Department of Medical Biology, The University of Melbourne, Parkville, 3010, Australia.
Dong X; The Walter and Eliza Hall Institute of Medical Research, Parkville, 3052, Australia.
Alhamdoosh M; Research and Development, CSL Limited, Bio21 Institute, Parkville, 3010, Australia.
Smyth GK; The Walter and Eliza Hall Institute of Medical Research, Parkville, 3052, Australia.
Ritchie ME; Department of Medical Biology, The University of Melbourne, Parkville, 3010, Australia.

F1000Res ; 9: 1444, 2020.

Article em En | MEDLINE | ID: mdl-33604029

Assuntos

Genômica; Expressão Gênica; Modelos Lineares; Análise de Sequência de RNA

Palavras-chave

Design matrix; contrast matrix; gene expression analysis; model matrix; statistical models

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Genômica Tipo de estudo: Prognostic_studies / Risk_factors_studies Idioma: En Ano de publicação: 2020 Tipo de documento: Article

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