In silico trials predict that combination strategies for enhancing vesicular stomatitis oncolytic virus are determined by tumor aggressivity.

Jenner, Adrianne L; Cassidy, Tyler; Belaid, Katia; Bourgeois-Daigneault, Marie-Claude; Craig, Morgan

Jenner, Adrianne L; Cassidy, Tyler; Belaid, Katia; Bourgeois-Daigneault, Marie-Claude; Craig, Morgan.

Afiliação

Jenner AL; Sainte-Justine University Hospital Research Centre, Montreal, Quebec, Canada.
Cassidy T; Department of Mathematics and Statistics, Université de Montréal, Montreal, Quebec, Canada.
Belaid K; Department of Mathematics and Statistics, McGill University, Montreal, Quebec, Canada.
Bourgeois-Daigneault MC; Theoretical Biology and Biophysics, Los Alamos National Laboratory, Los Alamos, New Mexico, USA.
Craig M; Department of Mathematics and Statistics, Université de Montréal, Montreal, Quebec, Canada.

J Immunother Cancer ; 9(2)2021 02.

Article em En | MEDLINE | ID: mdl-33608375

Assuntos

Neoplasias/terapia; Terapia Viral Oncolítica/métodos; Vaccinia virus/fisiologia; Vírus da Estomatite Vesicular Indiana/fisiologia; Simulação por Computador; Humanos; Gradação de Tumores; Neoplasias/patologia; Vírus Oncolíticos/fisiologia; Medicina de Precisão

Palavras-chave

clinical trials as topic; combination; computational biology; drug evaluation; drug therapy; oncolytic virotherapy; preclinical

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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Vaccinia virus / Vírus da Estomatite Vesicular Indiana / Terapia Viral Oncolítica / Neoplasias Tipo de estudo: Guideline / Prognostic_studies / Risk_factors_studies Limite: Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article

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