CoPIT; SARS-CoV-2 strains; astrocytes; biochemical reaction networks; bioinformatic analysis of proteomes; bottom up mass spectrometry; brain tissue; cell ontology; cellular microbiology; coronavirus; dendritic cells; emerging spike variants; extracellular matrix; fibroblasts; mast cells; megakaryocytes; monocytes; muscle; oligodendrocytes; protein folding; protein quality control; proteome analysis; structural biology modeling; unfolded protein response; virus host interactions; virus replication; virus variants