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The Role of Granulocyte Transfusions in Optimizing Candidacy for Chimeric Antigen Receptor T-cell Therapy in Patients With Treatment-refractory Infections.
Tambaro, Francesco P; Ragoonanan, Dristhi; Tewari, Priti; Petropoulos, Demetrios; Aung, Fleur M; Mahadeo, Kris M; Khazal, Sajad.
Afiliação
  • Tambaro FP; Department of Pediatrics, Pediatric Stem Cell Transplantation and Cellular Therapy, CARTOX Program.
  • Ragoonanan D; Bone Marrow Transplant Unit, Pediatric Oncology Department, AORN Santobono Pausilipon, Naples, Italy.
  • Tewari P; Department of Pediatrics.
  • Petropoulos D; Department of Pediatrics, Pediatric Stem Cell Transplantation and Cellular Therapy, CARTOX Program.
  • Aung FM; Department of Pediatrics, Pediatric Stem Cell Transplantation and Cellular Therapy, CARTOX Program.
  • Mahadeo KM; Department of Laboratory Medicine, Division of Pathology/Lab Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX.
  • Khazal S; Department of Pediatrics, Pediatric Stem Cell Transplantation and Cellular Therapy, CARTOX Program.
J Pediatr Hematol Oncol ; 44(2): e463-e466, 2022 Mar 01.
Article em En | MEDLINE | ID: mdl-33625094
ABSTRACT
While advancements in cellular therapy have improved outcomes for patients with refractory leukemia, severe infections may hinder access. Granulocyte transfusions, in combination with anti-microbial therapy, may be a safe option to facilitate candidacy for chimeric antigen receptor T-cell therapy in patients with leukemia and prolonged immune-compromised status.
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Texto completo: 1 Base de dados: MEDLINE Assunto principal: Leucemia / Receptores de Antígenos Quiméricos Limite: Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Leucemia / Receptores de Antígenos Quiméricos Limite: Humans Idioma: En Ano de publicação: 2022 Tipo de documento: Article