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Sialic acids in pancreatic cancer cells drive tumour-associated macrophage differentiation via the Siglec receptors Siglec-7 and Siglec-9.
Rodriguez, Ernesto; Boelaars, Kelly; Brown, Kari; Eveline Li, R J; Kruijssen, Laura; Bruijns, Sven C M; van Ee, Thomas; Schetters, Sjoerd T T; Crommentuijn, Matheus H W; van der Horst, Joost C; van Grieken, Nicole C T; van Vliet, Sandra J; Kazemier, Geert; Giovannetti, Elisa; Garcia-Vallejo, Juan J; van Kooyk, Yvette.
Afiliação
  • Rodriguez E; Amsterdam UMC, Vrije Universiteit Amsterdam, Department of Molecular Cell Biology and Immunology, Cancer Center Amsterdam, Amsterdam Infection and Immunity Institute, Amsterdam, Netherlands.
  • Boelaars K; Amsterdam UMC, Vrije Universiteit Amsterdam, Department of Molecular Cell Biology and Immunology, Cancer Center Amsterdam, Amsterdam Infection and Immunity Institute, Amsterdam, Netherlands.
  • Brown K; Amsterdam UMC, Vrije Universiteit Amsterdam, Department of Molecular Cell Biology and Immunology, Cancer Center Amsterdam, Amsterdam Infection and Immunity Institute, Amsterdam, Netherlands.
  • Eveline Li RJ; Amsterdam UMC, Vrije Universiteit Amsterdam, Department of Molecular Cell Biology and Immunology, Cancer Center Amsterdam, Amsterdam Infection and Immunity Institute, Amsterdam, Netherlands.
  • Kruijssen L; Amsterdam UMC, Vrije Universiteit Amsterdam, Department of Molecular Cell Biology and Immunology, Cancer Center Amsterdam, Amsterdam Infection and Immunity Institute, Amsterdam, Netherlands.
  • Bruijns SCM; Amsterdam UMC, Vrije Universiteit Amsterdam, Department of Molecular Cell Biology and Immunology, Cancer Center Amsterdam, Amsterdam Infection and Immunity Institute, Amsterdam, Netherlands.
  • van Ee T; Amsterdam UMC, Vrije Universiteit Amsterdam, Department of Molecular Cell Biology and Immunology, Cancer Center Amsterdam, Amsterdam Infection and Immunity Institute, Amsterdam, Netherlands.
  • Schetters STT; Amsterdam UMC, Vrije Universiteit Amsterdam, Department of Molecular Cell Biology and Immunology, Cancer Center Amsterdam, Amsterdam Infection and Immunity Institute, Amsterdam, Netherlands.
  • Crommentuijn MHW; Amsterdam UMC, Vrije Universiteit Amsterdam, Department of Molecular Cell Biology and Immunology, Cancer Center Amsterdam, Amsterdam Infection and Immunity Institute, Amsterdam, Netherlands.
  • van der Horst JC; Amsterdam UMC, Vrije Universiteit Amsterdam, Department of Molecular Cell Biology and Immunology, Cancer Center Amsterdam, Amsterdam Infection and Immunity Institute, Amsterdam, Netherlands.
  • van Grieken NCT; Amsterdam UMC, Vrije Universiteit Amsterdam, Department of Pathology, Amsterdam, Netherlands.
  • van Vliet SJ; Amsterdam UMC, Vrije Universiteit Amsterdam, Department of Molecular Cell Biology and Immunology, Cancer Center Amsterdam, Amsterdam Infection and Immunity Institute, Amsterdam, Netherlands.
  • Kazemier G; Amsterdam UMC, Vrije Universiteit Amsterdam, Department of Surgery, Cancer Center Amsterdam, Amsterdam, Netherlands.
  • Giovannetti E; Amsterdam UMC, Vrije Universiteit Amsterdam, Department of Medical Oncology, Cancer Center Amsterdam, Amsterdam, Netherlands.
  • Garcia-Vallejo JJ; Cancer Pharmacology Lab, AIRC Start-Up Unit, Fondazione Pisana per la Scienza, Pisa, Italy.
  • van Kooyk Y; Amsterdam UMC, Vrije Universiteit Amsterdam, Department of Molecular Cell Biology and Immunology, Cancer Center Amsterdam, Amsterdam Infection and Immunity Institute, Amsterdam, Netherlands.
Nat Commun ; 12(1): 1270, 2021 02 24.
Article em En | MEDLINE | ID: mdl-33627655

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Pâncreas / Neoplasias Pancreáticas / Ácidos Siálicos / Monócitos / Antígenos de Diferenciação Mielomonocítica / Antígenos CD / Lectinas Semelhantes a Imunoglobulina de Ligação ao Ácido Siálico / Lectinas / Macrófagos Tipo de estudo: Risk_factors_studies Limite: Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article

Texto completo: 1 Base de dados: MEDLINE Assunto principal: Pâncreas / Neoplasias Pancreáticas / Ácidos Siálicos / Monócitos / Antígenos de Diferenciação Mielomonocítica / Antígenos CD / Lectinas Semelhantes a Imunoglobulina de Ligação ao Ácido Siálico / Lectinas / Macrófagos Tipo de estudo: Risk_factors_studies Limite: Humans Idioma: En Ano de publicação: 2021 Tipo de documento: Article